ArticleScientific reports2023
Sulfur and nitrogen co-doped carbon quantum dots as fluorescent probes for the determination of some pharmaceutically-important nitro compounds.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Carbon Dots in Nanomedicine: Advanced Fabrication, Biomedical Applications, and Future Clinical Perspectives.Pharmaceutics · 2026Review
- A novel green QbD-optimized RP-HPLC bioanalytical method for the simultaneous determination of doxorubicin and rifampicin in human plasma.BMC chemistry · 2026Article
- Green "turn-off" luminescent nanosensor for the sensitive analysis of finerenone in various matrices: application of recent greenness assessment techniques.RSC advances · 2025Article
- Central composite design optimized fluorescent method using dual doped graphene quantum dots for lacosamide determination in biological samples.Scientific reports · 2025Article
- Eco-benign spectrofluorimetric analysis of icariin in a nano-formulation using green quantum dots: insights fromRSC advances · 2025Article
- Rational design and in vivo toxicity assessment of multichannel fluorescent carbon dots derived from Withania coagulans in Drosophila melanogaster.Mikrochimica acta · 2025Article
- Effective Determination of Diosmin Using Nitrogen Doped Carbon Dots as Probe Based on Internal Filtering Effect.Journal of fluorescence · 2025Review
- Ultrafast green synthesis of silver nanoparticles as fluorescent nanosensors for determination of isoniazid and nitrofurantoin in biological fluids and pharmaceuticals.Scientific reports · 2025Article
- Functionalized novel carbon dots from bell pepper seeds for sustainable green Edoxaban quantification.BMC chemistry · 2025Article
- Ultrasensitive turn-off fluorescent sensor for estimation of the new influenza antiviral prodrug baloxavir marboxil in its pharmaceutical formulation.Royal Society open science · 2025Article
- A review on carbon quantum dot/semiconductor-based nanocomposites as hydrogen production photocatalysts.RSC advances · 2024Review
- Inner-filter effect of nitrogen-doped carbon quantum dots-MnORSC advances · 2024Article
- Heteroatom-doped carbon dots from medicinal plants as novel biomaterials for as-use biomedical applications in comparison with synthetic drug, zaltoprofen.Scientific reports · 2024Article
- Novel Carbon Dots Derived fromInternational journal of nanomedicine · 2024Article
- White sustainable luminescent determination of nifuroxazide using nitrogen-sulphur co-doped carbon quantum dots nanosensor in bulk and various pharmaceutical matrices.RSC advances · 2023Article
- Green "turn-off" luminescent nanosensors for the sensitive determination of desperately fluorescent antibacterial antiviral agent and its metabolite in various matrices.Scientific reports · 2023Article
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Abstract
In this study, highly fluorescent sulfur and nitrogen co-doped carbon quantum dots (SN-CQDs) were synthesized by a simple one-pot hydrothermal method using thiosemicarbazide and citric acid as starting materials. Various spectroscopic and microscopic techniques were applied to characterize the prepared SN-CQDs. The synthesized SN-CQDs' maximum fluorescence emission was obtained at 430 nm after excitation at 360 nm. Rifampicin (RFP), tinidazole (TNZ), ornidazole (ONZ), and metronidazole (MNZ) all quantitatively and selectively quenched the SN-CQDs' native fluorescence, which was the base-for their-spectrofluorimetric estimation without the need for any tedious pre-treatment steps or high-cost instrumentation. SN-CQDs demonstrated a "turn-off" fluorescence response to RFP, TNZ, ONZ, and MNZ over the ranges of 1.0-30.0, 10.0-200.0, 6.0-200.0, and 5.0-100.0 μM with detection limits of 0.31, 1.76, 0.57, and 0.75 μM and quantitation limits of 0.93, 5.32, 1.74, and 2.28 μM respectively. The suggested method was successfully used to determine the investigated drugs in their commercial dosage forms. The method was further extended to their determination in spiked human plasma samples, with satisfactory mean % recoveries (99.44-100.29) and low % RSD values (< 4.52). The mechanism of fluorescence quenching was studied and discussed. The suggested method was validated in accordance with ICH recommendations.
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