Evidence map›Paper›PMID 37015823›Full record

ArticleNeurology2023

Burden of Common Neurologic Diseases in Asian Countries, 1990-2019: An Analysis for the Global Burden of Disease Study 2019.

Yue Wang, Jingjing Liang, Yuting Fang, Dongxiao Yao, Lily Zhang, Yanjie Zhou, Yajuan Wang, Luyu Hu, Zuneng Lu, Yilong Wang and 1 more

Abstract read
In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

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39citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Yue WangFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China. zmxiao@whu.edu.cn ylongwang@126.com.
Jingjing LiangFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China.
Yuting FangFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China.
Dongxiao YaoFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China.
Lily ZhangFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China.
Yanjie ZhouFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China.
Yajuan WangFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China. zmxiao@whu.edu.cn ylongwang@126.com.
Luyu HuFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China. zmxiao@whu.edu.cn ylongwang@126.com.
Zuneng LuFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China.
Yilong WangFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China. zmxiao@whu.edu.cn ylongwang@126.com.
Zheman XiaoFrom the Department of Neurology (Yue Wang, J.L., Y.F., L.Z., Y.Z., Yajuan Wang, L.H., Z.L., Z.X.), Renmin Hospital of Wuhan University; Department of Neurology (D.Y., Yilong Wang), Beijing Tiantan Hospital, Capital Medical University; Chinese Institute for Brain Research (Yilong Wang); China National Clinical Research Center for Neurological Diseases (Yilong Wang); Advanced Innovation Center for Human Brain Protection (Yilong Wang), Capital Medical University, Beijing; and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease (Yilong Wang), China. zmxiao@whu.edu.cn ylongwang@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesBased on the Global Burden of Diseases, Injuries, and Risk Factors (GBD) study, neurologic disorders are a major cause of morbidity and mortality worldwide. However, there has been no comprehensive assessment of neurologic disorders in Asia. Data from the GBD 1990-2019 study were investigated to provide new details for neurologic disorders in Asia.

methodsThe burden of common neurologic disorders in Asia was calculated for 1990 and 2019 as incidence, prevalence, deaths, and disability-adjusted life-years (DALYs). Thirteen common neurologic disorders were analyzed. Data are presented as totals and by sex, age, year, location, risk factors, and sociodemographic index (SDI) and shown as counts and rates.

resultsIn 2019, the most burdensome neurologic disorders in Asia for the absolute number of DALYs were stroke (98.8 million, 95% uncertainty interval [UI] 91.0-107.0), migraine (24.6 million, 95% UI 3.4-56.4), and Alzheimer disease (AD) and other dementias (13.5 million, 95% UI 5.9-29.8). From 1990 to 2019, the absolute number of DALYs and deaths caused by combined neurologic disorders (deaths by 60.7% and DALYs by 17.6%) increased, but the age-standardized rates (deaths by 34.1% and DALYs by 36.3%) decreased. The burden of neurologic disorders peaked among individuals aged 65-74 years and was higher among male than among female individuals; moreover, this burden varied considerably across Asian subregions and countries. Risk-attributable DALYs accounted for 86.9%, 28.5%, and 11.1% of DALYs for stroke, AD and other dementias, and multiple sclerosis, respectively. SDI was associated with both stroke and communicable neurological disorders. In terms of crude rate, the higher the SDI value, the higher the prevalence of stroke, and the lower all metrics of communicable neurological disorders. DISCUSSION: Neurologic disorders were the leading cause of DALYs and the second leading cause of deaths in Asia in 2019, and the burden may likely increase with the growth and aging of the Asian population. Urgent measures are needed for prevention, treatment, rehabilitation, and support services for common neurologic disorders regionally and nationally.

Indexed as

Alzheimer DiseaseNervous System DiseasesStrokeFemaleGlobal Burden of DiseaseGlobal HealthHumansMalePrevalenceQuality-Adjusted Life YearsRisk Factors

Identifiers

PMID37015823
PMCPMC10238164

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