Evidence map›Paper›PMID 37015307›Full record

ArticleAnnals of epidemiology2023

Birth weight moderates the association between obesity and mortality rate.

Gregory Pavela, Nengjun Yi, Luis Mestre, Pengcheng Xun, David B Allison

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gregory PavelaSchool of Public Health, University of Alabama at Birmingham, Birmingham. Electronic address: pavela@uab.edu.
Nengjun YiSchool of Public Health, University of Alabama at Birmingham, Birmingham.
Luis MestreSchool of Public Health, Indiana University Bloomington, Bloomington.
Pengcheng XunAtara Biotherapeutics, Thousand Oaks, CA.
David B AllisonSchool of Public Health, Indiana University Bloomington, Bloomington.
Indiana University Bloomington · USUniversity of Alabama at Birmingham · USAtara Biotherapeutics (United States) · US

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Obesity and Longevity Across GenerationsR01AG057703 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI ALLISON, DAVID B · 2018 to 2021
$1.1M
NIA NIH HHS R01 AG057703NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

purposeThe strength of the association between obesity and mortality rate (MR) varies by body mass index (BMI) and sociodemographic groups. We test the hypothesis that the association between obesity and MR varies, in part, due to the moderating effect of parental BMI and birth weight.

methodsData come from the 1958 National Child Development Study, an ongoing longitudinal dataset initiated in 1958 with baseline measures of birth weight from 18,059 infants born in Great Britain over 1 week. We tested whether the association between BMI and MR was moderated by parental BMI and birth weight using generalized additive proportional hazards models.

resultsThe association between adult BMI and MR was moderated by birth weight and maternal BMI, such that the association between BMI and MR was weaker among individuals with a higher birth weight (P = .0148) and stronger among individuals born to mothers with a higher BMI (P = .032). At any given level of BMI approximately greater than 25, individuals with low birth weight or born to mothers with a higher BMI, had a higher MR. Paternal BMI did not significantly modify the relationship between BMI and MR (P = .5168).

conclusionsResults suggest that the relationship between obesity and MR is modified by birth weight and maternal BMI.

Indexed as

MothersObesityAdultBirth WeightBody Mass IndexChildFemaleHumansInfantLongitudinal StudiesMaleBirth weightDevelopment origins of health and diseaseLife courseMortalityObesity

Identifiers

PMID37015307
PMCPMC10463462
OpenAlexW4362509173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.