ArticleClinics (Sao Paulo, Brazil)2023
β-catenin ameliorates myocardial infarction by preventing YAP-associated apoptosis.
Article in Clinics (Sao Paulo, Brazil), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Chrysin Attenuates Myocardial Cell Apoptosis in Mice.Cardiovascular toxicology · 2025Article
- YAP/TAZ as mechanobiological signaling pathway in cardiovascular physiological regulation and pathogenesis.Mechanobiology in medicine · 2024Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore whether the effect of β-catenin on MI and MI-induced cardiomyocyte apoptosis is YAP-dependent.
methodsThe authors established an MI rat model by ligating the anterior descending branch of the left coronary artery, and an MI cell model by treating cardiomyocytes with H
resultsβ-catenin downregulation was observed in MI cardiac tissues and in H
conclusionsThe present data indicate that β-catenin and YAP are effective treatment targets for MI, blocking the apoptotic death of cardiomyocytes.
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Registered trials
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