Evidence map›Paper›PMID 37014980›Full record

ArticleAnesthesiology2023

Patient and Process Outcomes among Pediatric Patients Undergoing Appendectomy during the COVID-19 Pandemic: An International Retrospective Cohort Study.

Clyde T Matava, Nathaniel T G Tighe, Reto Baertschiger, Robert T Wilder, Lynnie Correll, Steven J Staffa, David Zurakowski, Meredith A Kato, Petra M Meier, Vidya Raman and 10 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 5 countries.

Clyde T MatavaDepartment of Anesthesia and Pain Medicine, The Hospital for Sick Children. Toronto, Canada; Department of Anesthesiology and Pain Medicine, Faculty of Medicine, University of Toronto. Toronto, Canada.
Nathaniel T G TigheDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts.
Reto BaertschigerDepartment of Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
Robert T WilderDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Lynnie CorrellDepartment of Anesthesiology and Perioperative Medicine, University of Rochester, Rochester, New York.
Steven J StaffaDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts.
David ZurakowskiDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts.
Meredith A KatoOregon Health & Science University, Doernbecher Children's Hospital, Portland, Oregon.
Petra M MeierDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts.
Vidya RamanDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Srijaya K ReddyDepartment of Anesthesiology, Division of Pediatric Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Remigio A RoqueDepartment of Anesthesiology and Pain Medicine, Seattle Children's Hospital, Seattle, Washington.
Melissa Brooks PetersonDepartment of Anesthesiology, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.
John ZhongDepartment of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas; Department of Anesthesiology, Children's Health of Dallas, Dallas, Texas.
Thejovathi EdalaDepartment of Pediatric Anesthesiology, Arkansas Children's Hospital, Little Rock, Arkansas.
Timothy J GreerDepartment of Anaesthesia & Pain Management, Perth Children's Hospital, Perth, Western Australia, Australia.
Britta S von Ungern-SternbergDepartment of Anaesthesia & Pain Management, Perth Children's Hospital, Perth, Western Australia, Australia; Perioperative Medicine Team, Telethon Kids Institute, Perth, Western Australia, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, The University of Western Australia, Perth, Western Australia, Australia.
Joseph CraveroDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts.
Allan F SimpaoDepartment of Anesthesiology & Critical Care Medicine, Children's Hospital of Philadelphia. Philadelphia, Pennsylvania; Department of Anesthesiology & Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
PEACOC Collaborators
School of the Art Institute of Chicago · USBoston Children's Hospital · USArkansas Children's Hospital · USUniversity of Toronto · CAChildren's Hospital of Philadelphia · USMayo Clinic · USNationwide Children's Hospital · USSeattle Children's Hospital · USThe Kids Research Institute Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 forced healthcare systems to make unprecedented changes in clinical care processes. The authors hypothesized that the COVID-19 pandemic adversely impacted timely access to care, perioperative processes, and clinical outcomes for pediatric patients undergoing primary appendectomy.

methodsA retrospective, international, multicenter study was conducted using matched cohorts within participating centers of the international PEdiatric Anesthesia COVID-19 Collaborative (PEACOC). Patients younger than 18 yr old were matched using age, American Society of Anesthesiologists Physical Status, and sex. The primary outcome was the difference in hospital length of stay of patients undergoing primary appendectomy during a 2-month period early in the COVID-19 pandemic (April to May 2020) compared with prepandemic (April to May 2019). Secondary outcomes included time to appendectomy and the incidence of complicated appendicitis.

resultsA total of 3,351 cases from 28 institutions were available with 1,684 cases in the prepandemic cohort matched to 1,618 in the pandemic cohort. Hospital length of stay was statistically significantly different between the two groups: 29 h (interquartile range: 18 to 79) in the pandemic cohort versus 28 h (interquartile range: 18 to 67) in the prepandemic cohort (adjusted coefficient, 1 [95% CI, 0.39 to 1.61]; P < 0.001), but this difference was small. Eight centers demonstrated a statistically significantly longer hospital length of stay in the pandemic period than in the prepandemic period, while 13 were shorter and 7 did not observe a statistically significant difference. During the pandemic period, there was a greater occurrence of complicated appendicitis, prepandemic 313 (18.6%) versus pandemic 389 (24.1%), an absolute difference of 5.5% (adjusted odds ratio, 1.32 [95% CI, 1.1 to 1.59]; P = 0.003). Preoperative SARS-CoV-2 testing was associated with significantly longer time-to-appendectomy, 720 min (interquartile range: 430 to 1,112) with testing versus 414 min (interquartile range: 231 to 770) without testing, adjusted coefficient, 306 min (95% CI, 241 to 371; P < 0.001), and longer hospital length of stay, 31 h (interquartile range: 20 to 83) with testing versus 24 h (interquartile range: 14 to 68) without testing, adjusted coefficient, 7.0 (95% CI, 2.7 to 11.3; P = 0.002).

conclusionsFor children undergoing appendectomy, the COVID-19 pandemic did not significantly impact hospital length of stay. EDITOR’S PERSPECTIVE:

Indexed as

AppendicitisCOVID-19AppendectomyChildCOVID-19 TestingHumansLength of StayPandemicsPostoperative ComplicationsRetrospective StudiesSARS-CoV-2

Identifiers

PMID37014980
PMCPMC10246776
OpenAlexW4362593522

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.