Evidence map›Paper›PMID 37014466›Full record

ArticleJournal of cardiovascular translational research2024

FAM3A Deficiency - Induced Mitochondrial Dysfunction Underlies Post-Infarct Mortality and Heart Failure.

Tan Xu, Jiaxing Wang, Xiaoxiao Liu, Rui Xiang, Houhua Li, Shiqiang Wang, Jichun Yang, Ming Xu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Tan Xu *Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, China.
Jiaxing Wang *Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, China.
Xiaoxiao Liu *State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, China.
Rui XiangDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences of the Ministry of Education, Center for Non-Coding RNA Medicine, Peking University Health Science Center, Beijing, 100191, China.
Houhua LiState Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100191, China.
Shiqiang WangState Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, China.
Jichun YangDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences of the Ministry of Education, Center for Non-Coding RNA Medicine, Peking University Health Science Center, Beijing, 100191, China. yangj@bjmu.edu.cn.
Ming XuDepartment of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, China. xuminghi@bjmu.edu.cn.ORCID 0000-0003-1680-3628
Peking University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College 2021RU003Key Technologies Research and Development Program 2020YFA0803800Key Technologies Research and Development Program 2020YFA0803803National Natural Science Foundation of China 81900315National Natural Science Foundation of China 82270343National Natural Science Foundation of China U20A20345
6 · The paper itself

Abstract

Mitochondrial protein sequence similarity 3 gene family member A (FAM3A) plays important roles in the electron transfer chain, while its functions in the heart are still unknown. This study aims to explore the roles and mechanisms of FAM3A after myocardial infarction (MI). FAM3A-deficient (Fam3a

Indexed as

Heart FailureMitochondrial DiseasesMyocardial InfarctionAnimalsCytokinesMiceMitochondriaMitochondrial ProteinsMyocytes, CardiacCytokinesFAM3A protein, mouseMitochondrial ProteinsFAM3AHeart failureMitochondrial dysfunctionMyocardial infarctionOpa1

Identifiers

PMID37014466
OpenAlexW4362523473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.