Evidence map›Paper›PMID 37014272›Full record

ArticleAutophagy2023

LC3-independent autophagy is vital to prevent TNF cytotoxicity.

Dario Priem, Jon Huyghe, Mathieu Jm Bertrand

Abstract read
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Emerging mechanisms of ATG8-independent non-canonical autophagy.Journal of physiology and biochemistry · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Histone demethylases in autophagy and inflammation.Cell communication and signaling : CCS · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dario PriemCell Death and Inflammation Unit, VIB Center for Inflammation Research, Ghent, Belgium.ORCID 0000-0002-2527-1101
Jon HuygheCell Death and Inflammation Unit, VIB Center for Inflammation Research, Ghent, Belgium.ORCID 0000-0002-5306-5540
Mathieu Jm BertrandCell Death and Inflammation Unit, VIB Center for Inflammation Research, Ghent, Belgium.ORCID 0000-0001-9000-0626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The (macro)autophagy field is facing a paradigm shift after the recent discovery that cytosolic cargoes can still be selectively targeted to phagophores (the precursors to autophagosomes) even in the absence of LC3 or other Atg8-protein family members. Several

Indexed as

AutophagosomesAutophagyAnimalsAutophagy-Related Protein 8 FamilyMiceReceptors, Tumor Necrosis FactorTumor Necrosis FactorsAutophagy-Related Protein 8 FamilyReceptors, Tumor Necrosis FactorTumor Necrosis FactorsApoptosisATG9Acell deathembryogenesisLC3-independent autophagyskin disease

Identifiers

PMID37014272
PMCPMC10392734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.