Evidence map›Paper›PMID 37014244›Full record

ReviewRadiology2023

Imaging to Predict Prognosis in Hepatocellular Carcinoma: Current and Future Perspectives.

Maxime Ronot, Victoria Chernyak, Adam Burgoyne, Jeremy Chang, Hanyu Jiang, Mustafa Bashir, Kathryn J Fowler

Abstract readReview
PubMed Publisher
In one paragraph

Review in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Maxime RonotFrom the Department of Radiology, Université Paris Cité, Paris, France (M.R.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Departments of Medical Oncology (A.B.) and Internal Medicine (J.C.), University of California-San Diego, La Jolla, Calif; Department of Radiology, West China Hospital, Sichuan University, Chengdu, China (H.J.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); and Department of Radiology, University of California-San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F.).ORCID 0000-0001-7464-3939
Victoria ChernyakFrom the Department of Radiology, Université Paris Cité, Paris, France (M.R.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Departments of Medical Oncology (A.B.) and Internal Medicine (J.C.), University of California-San Diego, La Jolla, Calif; Department of Radiology, West China Hospital, Sichuan University, Chengdu, China (H.J.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); and Department of Radiology, University of California-San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F.).ORCID 0000-0002-5715-1403
Adam BurgoyneFrom the Department of Radiology, Université Paris Cité, Paris, France (M.R.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Departments of Medical Oncology (A.B.) and Internal Medicine (J.C.), University of California-San Diego, La Jolla, Calif; Department of Radiology, West China Hospital, Sichuan University, Chengdu, China (H.J.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); and Department of Radiology, University of California-San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F.).
Jeremy ChangFrom the Department of Radiology, Université Paris Cité, Paris, France (M.R.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Departments of Medical Oncology (A.B.) and Internal Medicine (J.C.), University of California-San Diego, La Jolla, Calif; Department of Radiology, West China Hospital, Sichuan University, Chengdu, China (H.J.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); and Department of Radiology, University of California-San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F.).ORCID 0000-0002-5514-6563
Hanyu JiangFrom the Department of Radiology, Université Paris Cité, Paris, France (M.R.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Departments of Medical Oncology (A.B.) and Internal Medicine (J.C.), University of California-San Diego, La Jolla, Calif; Department of Radiology, West China Hospital, Sichuan University, Chengdu, China (H.J.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); and Department of Radiology, University of California-San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F.).ORCID 0000-0002-7726-1618
Mustafa BashirFrom the Department of Radiology, Université Paris Cité, Paris, France (M.R.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Departments of Medical Oncology (A.B.) and Internal Medicine (J.C.), University of California-San Diego, La Jolla, Calif; Department of Radiology, West China Hospital, Sichuan University, Chengdu, China (H.J.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); and Department of Radiology, University of California-San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F.).ORCID 0000-0001-8800-5057
Kathryn J FowlerFrom the Department of Radiology, Université Paris Cité, Paris, France (M.R.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Departments of Medical Oncology (A.B.) and Internal Medicine (J.C.), University of California-San Diego, La Jolla, Calif; Department of Radiology, West China Hospital, Sichuan University, Chengdu, China (H.J.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); and Department of Radiology, University of California-San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F.).ORCID 0000-0001-9188-1701

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The focus of hepatocellular carcinoma (HCC) research for many years has been on noninvasive diagnosis. Standardized systematic algorithms composed of combinations of precise features now serve as diagnostic imaging markers of HCC and constitute a major innovation for liver imaging. In clinical practice, the diagnosis of HCC is based primarily on imaging and secondarily on pathologic analysis if the imaging features are not specific. Whereas accurate diagnosis is essential, the next phase of innovation for HCC will likely encompass predictive and prognostic markers. HCC is a biologically heterogeneous malignancy because of complex molecular, pathologic, and patient-level factors that impact the outcomes of treatment. In recent years, there have been many advances in systemic therapy to augment and extend the existing large cache of local and regional options. However, the guideposts for treatment decisions are neither sophisticated nor individualized. This review provides an overview of prognosis in HCC from the patient to the imaging feature level with a focus on future directions toward more individualized treatment guidance.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsDiagnostic ImagingHumansPrognosis

Identifiers

PMID37014244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.