Evidence map›Paper›PMID 37014212›Full record

ArticleInfection and immunity2023

Copper Efflux System Required in Murine Lung Infection by Haemophilus influenzae Composed of a Canonical ATPase Gene and Tandem Chaperone Gene Copies.

Sandy M Wong, Jeffrey Gawronski, Brian J Akerley

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Copper-chelating natural products.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Review
  4. A multi-iron enzyme installs copper-binding oxazolone/thioamide pairs on a nontypeableProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sandy M Wong *Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Jeffrey Gawronski *Department of Microbiology and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Brian J AkerleyDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA.ORCID 0000-0002-8142-7035
University of Mississippi Medical Center · USUniversity of Massachusetts Chan Medical School · US

Funding

Mechanisms of Haemophilus influenzae pathogenesis in the lungR01AI095740 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI AKERLEY, BRIAN, SHEN, HAO · 2012 to 2016
$1.8M
NIAID NIH HHS R01 AI095740
6 · The paper itself

Abstract

Copper is an essential micronutrient but is toxic at high concentrations. In Haemophilus influenzae mechanisms of copper resistance and its role in pathogenesis are unknown; however, our previous genetic screen by transposon insertion-site sequencing implicated a putative cation transporting ATPase (

Indexed as

CopperMetallochaperonesAdenosine TriphosphatasesAnimalsBacterial ProteinsDisease Models, AnimalHaemophilus influenzaeLungMiceAdenosine TriphosphatasesBacterial ProteinsCopperMetallochaperonesantimicrobial agentscopAcoppercopZefflux pumpsHaemophilus influenzaelung infectionmouse modelNTHi

Identifiers

PMID37014212
PMCPMC10187127
OpenAlexW4362520937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.