Evidence map›Paper›PMID 37014126›Full record

ReviewFEBS open bio2023

Glycosphingolipids within membrane contact sites influence their function as signaling hubs in neurodegenerative diseases.

Jason Andrew Weesner, Ida Annunziata, Diantha van de Vlekkert, Alessandra d'Azzo

Open access · goldAbstract readReview
In one paragraph

Review in FEBS open bio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Impacts of Globo H Ceramide on Tumor Microenvironment.Advances in experimental medicine and biology · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Metabolic Markers and Association of Biological Sex in Lupus Nephritis.International journal of molecular sciences · 2023
    Article
  7. Article
  8. Sphingolipids in mitochondria-from function to disease.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jason Andrew WeesnerDepartment of Genetics, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-0630-1715
Ida AnnunziataDepartment of Genetics, St. Jude Children's Research Hospital, Memphis, TN, USA.
Diantha van de VlekkertDepartment of Genetics, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0001-7498-1292
Alessandra d'AzzoDepartment of Genetics, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0003-1747-7502
St. Jude Children's Research Hospital · US

Funding

Dissecting the role of NEU1-dependent de-sialylation in neurodegeneration and neuroinflammationRF1NS123174 · NINDS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI D'AZZO, ALESSANDRA · 2021 to 2021
$1.8M
NINDS NIH HHS RF1 NS123174
6 · The paper itself

Abstract

Intracellular organelles carry out many of their functions by engaging in extensive interorganellar communication through specialized membrane contact sites (MCSs) formed where two organelles tether to each other or to the plasma membrane (PM) without fusing. In recent years, these ubiquitous membrane structures have emerged as central signaling hubs that control a multitude of cellular pathways, ranging from lipid metabolism/transport to the exchange of metabolites and ions (i.e., Ca

Indexed as

GlycosphingolipidsNeurodegenerative DiseasesEndoplasmic ReticulumHumansIntracellular MembranesMitochondriaGlycosphingolipidsendo-lysosomeERglycosphingolipidslysosomal storage diseasesmembrane contact sitesmitochondria

Identifiers

PMID37014126
PMCPMC10476575
OpenAlexW4362524013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.