Evidence map›Paper›PMID 37013994›Full record

Observational studyCartilage2023

Anterior Tibiotalar Fat Pad Involvement in Ankle Osteoarthritis: MRI Features in Patients 1 Year After a Lateral Ankle Sprain.

Stijn Arnaert, Paul Byttebier, Sam Van Rossom, Evie Vereecke, Ilse Jonkers, Edwin Oei, Sita M A Bierma-Zeinstra, Rik Lories, Marienke van Middelkoop, Stefan Clockaerts

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Cartilage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. [Correlation analysis of anterior tibiotalar fat pad classification and anterior talofibular ligament injury based on MRI].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Stijn ArnaertDivision of Internal Medicine, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-1785-9415
Paul ByttebierOrthopedic Surgery and Traumatology, General Municipal Hospital Aalst, Aalst, Belgium.
Sam Van RossomHuman Movement Biomechanics Research Group, KU Leuven, Leuven, Belgium.
Evie VereeckeDepartment of Development and Regeneration, KU Leuven, Kortrijk, Belgium.
Ilse JonkersHuman Movement Biomechanics Research Group, KU Leuven, Leuven, Belgium.
Edwin OeiRadiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Sita M A Bierma-ZeinstraGeneral Practice, Erasmus University Medical Center, Rotterdam, The Netherlands.
Rik LoriesDivision of Rheumatology, University Hospitals Leuven, Leuven, Belgium.
Marienke van MiddelkoopGeneral Practice, Erasmus University Medical Center, Rotterdam, The Netherlands.
Stefan ClockaertsDepartment of Development and Regeneration, Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium.
KU Leuven · BEErasmus MC · NLOnze Lieve Vrouwziekenhuis Hospital · BEUniversity College West Flanders · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the characteristics of the anterior tibiotalar fat pad (ATFP) in the ankle joint in a population of patients 1 year after an ankle sprain and its correlation with systemic factors and local articular pathology.

designThe study is a secondary analysis of an observational case-control study. We included 206 patients who were followed 6-12 months after ankle sprain. T1 MRI scans were assessed for signal intensity and area of ATFP by mapping the fat pad using dedicated imaging software (Mimics 18.0). Quantitative values of intensity and area were generated. Linear regression analysis was used to examine the association between both local and systemic factors and the ATFP. Variables with a

resultsThe final multivariate model showed a significant positive association between age (

conclusionThis study demonstrates a correlation between ATFP and both systemic factors and local pathology in the ankle joint.

Indexed as

Ankle InjuriesOsteoarthritisAdipose TissueAnkleAzidesCase-Control StudiesHumansMagnetic Resonance Imaging4-azido-2,3,5,6-tetrafluoropyridineAzidesankle osteoarthritisankle sprainfat padMRI

Identifiers

PMID37013994
PMCPMC10601560
OpenAlexW4362521020

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.