Evidence map›Paper›PMID 37013620›Full record

SynthesisJournal of orthopaedic surgery and research2023

Comparison of three common shoulder injections for rotator cuff tears: a systematic review and network meta-analysis.

Xinzhao Jiang, Hong Zhang, Qing Wu, Yun Chen, Tian Jiang

Registry-linked trialOpen access · goldAbstract readSystematic ReviewNetwork Meta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07659600 (Performance of Autologous Platelet-rich Plasma Injection for Tendon Regeneration in Partial Supraspinatus Tears), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07659600 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Performance of Autologous Platelet-rich Plasma Injection for Tendon Regeneration in Partial Supraspinatus Tears

TypeinterventionalSponsorUniversidade Nova de LisboaRan2026 to 2029Enrolled100ConditionsPartial Supraspinatus Tear, Rotator Cuff Tears (RCTs), Rotator Cuff InjuryArmsPlatelet-Rich Plasma (PRP) Injections
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xinzhao JiangDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Hong ZhangDepartment of Pain Management, Jiangyin People's Hospital Affiliated to Nantong University, Wuxi, 214400, China.
Qing WuDepartment of Pain Management, Jiangyin People's Hospital Affiliated to Nantong University, Wuxi, 214400, China.
Yun ChenDepartment of Pain Management, Jiangyin People's Hospital Affiliated to Nantong University, Wuxi, 214400, China.
Tian JiangDepartment of Pain Management, Jiangyin People's Hospital Affiliated to Nantong University, Wuxi, 214400, China. jtwmj2000@aliyun.com.
Nantong University · CNFirst Affiliated Hospital of Soochow University · CNJiangyin People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the clinical effectiveness of three common shoulder injections mentioned in the guidelines [corticosteroid, sodium hyaluronate (SH) and platelet-rich plasma (PRP)] on rotator cuff tears. MATERIAL AND

methodsThe PubMed, Embase and Cochrane Library databases were systematically searched up to June 1, 2022, for randomized controlled trials (RCTs) and prospective studies on the three injection therapies for rotator cuff tears. The main results were pain relief and functional improvement at 1-5 months and over 6 months, pooled using a network meta-analysis and ranked by SUCRA score. The risk of bias of the included studies was assessed using the Cochrane Collaboration tool.

resultsTwelve RCTs and 4 prospective studies comprising a total of 1115 patients were included in the review. Three prospective studies were judged to be at high risk of selection bias and performance bias, and one was considered as having a high risk of detection bias. SH injection ranked first in the short term in pain relief (MD: - 2.80; 95%CI - 3.91, - 1.68) and functional improvement (MD:19.17; 95%CI 12.29, 26.05), while PRP injection obtained better results in the long term in both pain relief (MD: - 4.50; 95%CI - 4.97, - 4.03) and functional improvement (MD:11.11; 95%CI 0.53,21.68).

conclusionsPRP injection has the potential to successfully treat rotator cuff tears as an alternative to corticosteroids in the long term, in terms of either therapeutic efficiency or adverse effects, followed by SH injection. More research is needed to make high-quality recommendations on treatment options for injection treatments of rotator cuff tears.

Indexed as

Platelet-Rich PlasmaRotator Cuff InjuriesAdrenal Cortex HormonesHumansHyaluronic AcidInjections, Intra-ArticularPainShoulderTreatment OutcomeAdrenal Cortex HormonesHyaluronic AcidCorticosteroidHyaluronic acidNetwork meta-analysisPlatelet-rich plasmaRotator cuff tear

Identifiers

PMID37013620
PMCPMC10069022
OpenAlexW4362522357

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.