Evidence map›Paper›PMID 37013506›Full record

ArticleBMC public health2023

Overall lifestyle changes in adulthood are associated with cancer incidence in the Norwegian Women and Cancer Study (NOWAC) - a prospective cohort study.

Sairah L F Chen, Therese H Nøst, Edoardo Botteri, Pietro Ferrari, Tonje Braaten, Torkjel M Sandanger, Kristin B Borch

Abstract read
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In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sairah L F ChenDepartment of Community Medicine, UiT The Arctic University of Norway, Hansine Hansens Veg 18, 9019, Tromsø, Norway. sairah.chen@uit.no.ORCID 0000-0001-5774-7058
Therese H NøstDepartment of Community Medicine, UiT The Arctic University of Norway, Hansine Hansens Veg 18, 9019, Tromsø, Norway.
Edoardo BotteriDepartment of Research, Cancer Registry of Norway, Ullernchauseen 64, 0379, Oslo, Norway.
Pietro FerrariNutrition and Metabolism Branch, International Agency for Research On Cancer, World Health Organization, World Health Organization, 150 Cours Albert Thomas, 69372 CEDEX 08, Lyon, France.
Tonje BraatenDepartment of Community Medicine, UiT The Arctic University of Norway, Hansine Hansens Veg 18, 9019, Tromsø, Norway.
Torkjel M SandangerDepartment of Community Medicine, UiT The Arctic University of Norway, Hansine Hansens Veg 18, 9019, Tromsø, Norway.
Kristin B BorchDepartment of Community Medicine, UiT The Arctic University of Norway, Hansine Hansens Veg 18, 9019, Tromsø, Norway.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundCancer is a leading cause of premature death worldwide and incidence is expected to rise in the coming decades. Many cohort studies, measuring lifestyle factors at one time-point, have observed that overall healthy lifestyles were inversely related to cancer incidence. However, there is little knowledge on the impact of lifestyle modification within adulthood.

methodsUsing the Norwegian Women and Cancer study, two repeated self-reported assessments of lifestyle behaviours were used to calculate healthy lifestyle index scores at each time-point (N = 66 233). The associations between change in healthy lifestyle index score and lifestyle-related cancer incidence, including alcohol-, tobacco-, obesity-, and reproductive-related, and site-specific breast and colorectal cancer incidence were estimated using Cox proportional hazard regression models. To assess nonlinearity in the dose-response relationships, restricted cubic spline models were used.

resultsIndependent of baseline lifestyle, positive lifestyle changes were inversely related to the incidence of overall lifestyle-related cancers, as well as alcohol-related, tobacco-related, obesity-related, and reproductive-related cancers, but not breast and colorectal site-specific cancers. An association between lifestyle worsening and cancer incidence compared to stable lifestyle was observed.

conclusionsThis study provides evidence that overall lifestyle changes among cancer-free women between the ages of 41 and 76 impact the incidence of many cancer types. Regardless of baseline lifestyle, there was a negative dose-response relationship between magnitude of positive lifestyle change and the incidence of overall lifestyle-related cancers. We observed that underlying this trend was an especially clear association between lifestyle worsening and increased risk compared to stable lifestyle. For adult women, maintaining a stable healthy lifestyle and lifestyle improvement are important for preventing the occurrence of many cancer types.

Indexed as

NeoplasmsAdultAgedCohort StudiesFemaleHealthy LifestyleHumansIncidenceLife StyleMiddle AgedNorwayObesityProspective StudiesRisk FactorsCancerChangeCohortComposite indexLifestylePreventionRepeated measurementsWomen

Identifiers

PMID37013506
PMCPMC10069035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.