Evidence map›Paper›PMID 37013487›Full record

ArticleBMC anesthesiology2023

Opioid-sparing anesthesia with dexmedetomidine provides stable hemodynamic and short hospital stay in non-intubated video-assisted thoracoscopic surgery: a propensity score matching cohort study.

Hui-Hsuan Ke, Jing-Yang Liou, Wei-Nung Teng, Po-Kuei Hsu, Mei-Yung Tsou, Wen-Kuei Chang, Chien-Kun Ting

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hui-Hsuan KeDepartment of Anesthesiology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Jing-Yang LiouDepartment of Anesthesiology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Wei-Nung TengDepartment of Anesthesiology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Po-Kuei HsuDepartment of Anesthesiology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Mei-Yung TsouDepartment of Anesthesiology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Wen-Kuei ChangDepartment of Anesthesiology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chien-Kun TingDepartment of Anesthesiology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. ckting2@gmail.com.
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDexmedetomidine is an alpha-2 agonist with anti-anxiety, sedative, and analgesic effects and causes a lesser degree of respiratory depression. We hypothesized that the use of dexmedetomidine in non-intubated video-assisted thoracic surgery (VATS) may reduce opioid-related complications such as postoperative nausea and vomiting (PONV), dyspnea, constipation, dizziness, skin itching, and cause minimal respiratory depression, and stable hemodynamic status.

methodsPatients who underwent non-intubated VATS lung wedge resection with propofol combined with dexmedetomidine (group D) or alfentanil (group O) between December 2016 and May 2022 were enrolled in this retrospective propensity score matching cohort study. Intraoperative vital signs, arterial blood gas data, perioperative results and treatment outcomes were analyzed. Of 100 patients included in the study (group D, 50 and group O, 50 patients), group D had a significantly lower degree of decrement in the heart rate and the blood pressure than group O. Intraoperative one-lung arterial blood gas revealed lower pH and significant ETCO

conclusionsThe application of dexmedetomidine in non-intubated VATS resulted in a significant reduction in perioperative opioid-related complications and maintenance with acceptable hemodynamic performance. These clinical outcomes found in our retrospective study may enhance patient satisfaction and shorten the hospital stay.

Indexed as

AnesthesiaDexmedetomidineRespiratory InsufficiencyAnalgesics, OpioidCohort StudiesDizzinessDyspneaHemodynamicsHumansLength of StayPostoperative Nausea and VomitingPostoperative PainPropensity ScoreRetrospective StudiesThoracic Surgery, Video-AssistedAnalgesics, OpioidDexmedetomidineDexmedetomidineHemodynamic stabilityHospital stayNon-intubated video-assisted thoracic surgeryOpioid-related complications

Identifiers

PMID37013487
PMCPMC10069055
OpenAlexW4362521148

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.