ArticleBMC ophthalmology2023
Influence of overnight orthokeratology on tear film and meibomian glands in myopic children: a prospective study.
Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Adjunctive Eyelid Hygiene Improves Early Adaptation to Pediatric Orthokeratology: A Randomized Clinical Study.Eye & contact lens · 2026Trial
- Development and validation of a risk prediction model for dry eye disease in myopic children.Frontiers in medicine · 2026Article
- Diagnostic methods for managing dry eyes.World journal of methodology · 2025Article
- AI-Based Estimate of the Regional Effect of Orthokeratology Lenses on Tear Film Quality.Bioengineering (Basel, Switzerland) · 2025Article
- Risk factors and nomogram-based prediction of dry eye disease following intraocular lens implantation in cataract patients.BMC ophthalmology · 2025Article
- The Distribution and Influence Factors of Non-Invasive Tear Film Break-Up Time in Children [Letter].Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- The application of hyaluronic acid-containing artificial tears on the ocular surface of children receiving orthokeratology contact lens treatment.International journal of medical sciences · 2025Article
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3 authors.
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Abstract
backgroundOrthokeratology lenses, which are worn overnight, are recommended for reducing myopia progression. They lie on the cornea and can influence the ocular surface by temporarily reshaping the corneal surface through a reverse geometry design. This study investigated the effect of overnight orthokeratology lenses on tear film stability and meibomian gland status in children aged 8-15 years.
methodsThis prospective, self-controlled study included 33 children with monocular myopia who were prescribed orthokeratology lenses for at least one year. The experimental group (ortho-k group) comprised 33 myopic eyes. The control group comprised the emmetropic eyes of the same participants. Tear film stability and meibomian gland status were measured using a Keratograph 5M (Oculus, Wetzlar, Germany). Paired t-tests and Wilcoxon signed-rank tests were used to compare the data between the two groups.
resultsAt the one-year visit, the non-invasive first tear film break-up time (NIBUTf) values were 6.15 ± 2.56 s and 6.18 ± 2.61 s in the experimental and control groups, respectively. The lower tear meniscus height was 18.74 ± 0.05 μm and 18.65 ± 0.04 μm in these groups, respectively. No significant difference was observed in loss of meibomian glands or non-invasive average tear film break-up time between the experimental and control groups using Wilcoxon signed-rank tests.
conclusionsThe stability of the tear film and meibomian gland status were not significantly affected by wearing orthokeratology lenses overnight, indicating that continuous use of orthokeratology lenses for 12 months has a minimal effect on the ocular surface. This finding can help guide the clinical management of tear film quality with respect to the use of orthokeratology contact lenses.
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