Evidence map›Paper›PMID 37013374›Full record

ArticleeLife2023

Defining basic rules for hardening influenza A virus liquid condensates.

Temitope Akhigbe Etibor, Silvia Vale-Costa, Sindhuja Sridharan, Daniela Brás, Isabelle Becher, Victor Hugo Mello, Filipe Ferreira, Marta Alenquer, Mikhail M Savitski, Maria-João Amorim

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

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  5. How Oncovirus Affects Drug Resistance in Cancer Cells.Recent patents on anti-cancer drug discovery · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Temitope Akhigbe EtiborCell Biology of Viral Infection Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID 0000-0002-9024-4310
Silvia Vale-CostaCell Biology of Viral Infection Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Sindhuja SridharanEuropean Molecular Biology Laboratory, Heidelberg, Germany.
Daniela BrásCell Biology of Viral Infection Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Isabelle BecherEuropean Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0001-7170-2235
Victor Hugo MelloCell Biology of Viral Infection Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Filipe FerreiraCell Biology of Viral Infection Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Marta AlenquerCell Biology of Viral Infection Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID 0000-0003-3062-1222
Mikhail M SavitskiEuropean Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0003-2011-9247
Maria-João AmorimCell Biology of Viral Infection Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID 0000-0002-4129-6659
Instituto Gulbenkian de Ciência · PTEuropean Molecular Biology Laboratory · DEUniversidade Católica Portuguesa · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In biological systems, liquid and solid-like biomolecular condensates may contain the same molecules but their behaviour, including movement, elasticity, and viscosity, is different on account of distinct physicochemical properties. As such, it is known that phase transitions affect the function of biological condensates and that material properties can be tuned by several factors including temperature, concentration, and valency. It is, however, unclear if some factors are more efficient than others at regulating their behaviour. Viral infections are good systems to address this question as they form condensates

Indexed as

Influenza A virusVirus DiseasesAntiviral AgentsHumansRibonucleoproteinsVirus ReplicationAntiviral AgentsRibonucleoproteinsbiomolecular condensateshumaninfectious diseaseinfluenza A virusmicrobiologymousephase transitionsphysics of living systemsproteome-wide solubilityviral inclusionsviruses

Identifiers

PMID37013374
PMCPMC10154025
OpenAlexW4362522909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.