Evidence map›Paper›PMID 37013353›Full record

ArticleInternational journal of surgical pathology2023

A Case of Mediastinal Carcinosarcoma With Beta-HCG Production and KRAS Mutation.

Nada Shaker, Chiemezie C Amadi, Meng Welliver, Gregory A Otterson, David A Liebner, Konstantin Shilo

Open access · hybridAbstract readCase Reports
In one paragraph

Article in International journal of surgical pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nada ShakerDepartment of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID 0000-0001-6145-256X
Chiemezie C AmadiDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Meng WelliverDivision of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Gregory A OttersonDivision of Medical Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
David A LiebnerDivision of Medical Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Konstantin ShiloDepartment of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID 0000-0002-6702-3130
The Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carcinosarcomas of mediastinum are rare and only few well-documented cases are available in the literature. We report a detailed description of mediastinal carcinosarcoma with unique clinical manifestations and immunohistochemical and molecular profiles. A 44-year-old female with an enlarging anterior mediastinal mass was found to have a positive pregnancy test. Thoracoscopic biopsy revealed that the mass represented a carcinosarcoma with adenocarcinoma and chondrosarcoma components. The tumor focally expressed beta-HCG by immunohistochemistry and had

Indexed as

AdenocarcinomaCarcinosarcomaAdultFemaleHumansMediastinumMutationPregnancyProto-Oncogene Proteins p21(ras)KRAS protein, humanProto-Oncogene Proteins p21(ras)beta-subunit of human chorionic gonadotropincarcinosarcomaKRAS mutationmediastinumsarcomatoid carcinomathymus

Identifiers

PMID37013353
PMCPMC10616989
OpenAlexW4362521537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.