ArticleJournal of the American Geriatrics Society2023
Factors affecting the recruitment of Hispanic/Latinx American older adults in clinical trials in the United States: A scoping review.
Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Strategies to reach, involve, and maintain underserved populations in health intervention research: a systematic review of reviews.International journal for equity in health · 2026Pooled it
- Success and cost-effectiveness of strategies to recruit older adults to a behavioral intervention research study.Contemporary clinical trials · 2025Trial
- Access to translated invitations online increases involvement of linguistically diverse households in a population-based study: a cluster randomized controlled study.Scientific reports · 2025Trial
- Usability and Cultural Relevance of an mHealth App for Hispanic/Latino Individuals Living With Rheumatoid Arthritis: Protocol for a Mixed Methods Study.JMIR research protocols · 2026Article
- Cognitive ageing among older Latin American immigrants: current evidence and limitations.Frontiers in aging neuroscience · 2026Review
- Article
- Key considerations and recommendations for recruiting older adults in physical activity studies.BMC medical research methodology · 2025Article
- Using a Community-Based Participatory Research Approach to Study the Mental Health of Older Adults with a Refugee Life Experience.International journal of environmental research and public health · 2025Article
- Después del Cáncer: a qualitative exploration of navigating survivorship as a Latino couple following a breast cancer diagnosis.Journal of cancer survivorship : research and practice · 2025Article
- Optimizing recruitment strategies for healthy older adults in prevention clinical trials: A scoping review.Journal of clinical and translational science · 2025Review
- National Institute on Aging efforts toward ensuring representation of diverse older adults in clinical studies.Journal of the American Geriatrics Society · 2024Article
- The Multi-Institutional Medullary Thyroid Cancer Collaborative Registry: Can a Rare Tumor Registry Accurately Represent the Real-World Patient Population?Thyroid : official journal of the American Thyroid Association · 2024Article
- Recruitment and retention of clinical trial participants: understanding motivations of patients with chronic pain and other populations.Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- Recruitment of mid-life adults to a randomized clinical trial: The multicultural healthy diet study to reduce cognitive decline and Alzheimer's disease risk.Alzheimer's & dementia (New York, N. Y.)Article
- Digital efforts in Spanish for enrolling Latino adults in the Brain Health Registry.Alzheimer's & dementia (New York, N. Y.)Article
- Engaging Hispanic/Latino young adults in Alzheimer's disease research through boot camp translation.Alzheimer's & dementia (New York, N. Y.)Article
- Decentralizing dementia research to the US-Mexico border: the Rio Grande Valley AD-RCMAR as a model for translational equity.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveParticipation of Hispanic/Latinx American older adults (HLAOA) in clinical trials is fundamental to health equity in aging research. However, information on strategies for the successful recruitment of this population in clinical trials is limited.
designThis scoping review aims to identify hindering and facilitating factors that impact the recruitment of HLAOA in clinical trials in the United States.
methodsTwo databases (PubMed, EMBASE) were searched for original research articles from inception until March 2022 reporting on factors that engaged HLAoa (≥65) in clinical trials. One thousand and thirteen studies were scrutinized to identify 31 eligible articles.
resultsMost articles were from cancer clinical trials (14 studies). Hindering factors that impacted the recruitment of HLAoa in clinical trials were related to (i) study design and logistics challenges, (ii) challenges imposed by social determinants of health, (iii) communication barriers, and (iv) patients' mistrust, and (v) family issues. Facilitating factors include (i) effective modes of outreach, (ii) strategic clinical trial design, (iii) incorporating culturally-respectful approaches that are tailored to the participants' sociocultural background, and (iv) bridging language barriers.
conclusionsSuccessful recruitment of HLAOA into clinical trials requires identifying the study question, co-designing the trial design, implementation, and evaluation in respectful collaboration with the Hispanic/Latinx community with careful attention to their needs and minimizing the study burden on this vulnerable population. Factors identified here may guide researchers to better understand the needs of HLAOA and successfully recruit them into clinical trials, leading to more equitable research that increases their representation in clinical research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.