Trial reportJournal of orthopaedic case reports2022
Clinical use of Plasma Protein from Platelet in Degenerative Joint Disease: A Prospective Study.
Trial report in Journal of orthopaedic case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.
- Efficacy and safety of platelet-rich plasma injections for the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.European journal of medical research · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Plasma rich in protein derived from platelets also known as platelet-rich plasma (PRP) is a recent science being used in many fields of medicine including cosmetic and musculoskeletal treatment. It has a very good ability to promote healing and decrease pain when added to certain treatment protocols. Being a simple and minimally invasive method of treatment, it is over-looked as a treatment option for the early osteoarthritis (OA) of knee joint. Well-designed randomized controlled studies and research are needed to measure outcomes, durability of effect while being cost effective. Aim of the Research Study: The aim of this study was to prove the use of PRP and its outcome in the clinical treatment of arthritic joint diseases of knee, progression of disease in people treated for early stage OA, and functional outcome of PRP injection in knee degenerative diseases. Materials and Methods: This study was study period-6 months, sample size-50, sample type-patient, and functional outcome assessed using knee osteoarthritis outcome score (KOOS). Methodology of Research Work: This study was aimed to prospectively quantify the effect of treatment with platelet-rich plasma (PRP) injection in patients with degenerative joint diseases. Degenerative joint disease treated using PRP injections with an average study period of 6 months was analyzed according to measure of pain at baseline and post-treatment using KOOS. Data Analysis: Collected data will be analyzed by SPSS Software Version 19. Primary Objective: PRP injections aim to relieve pain and to improve functional status of the patient. Results: PRP is effective with treatment for degenerative knee arthritis. The patients found excellent relief in pain and mobility. The range of movement and KOOS score was found to be improved with P < 0.001.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.