Evidence map›Paper›PMID 37012949›Full record

ArticleCureus2023

Macrophage Activation Syndrome (MAS): A Case Report and Narrative Review.

Arthur Dilibe, Onyinye S Ugoala, Endurance O Evbayekha, Mohammad Z Khalilullah, Olanrewaju K Adabale, Tracy-Ann Poyser, Osejie F Oriaifo, Ufuoma I Olori, Henry O Aiwuyo

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Marginal Zone Lymphoma Manifesting as Macrophage Activation Syndrome: A Case Report.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Arthur DilibeInternal Medicine, Brody School of Medicine at East Carolina University, Greenville, USA.
Onyinye S UgoalaInternal Medicine, College of Medicine, University of Lagos, Lagos, NGA.
Endurance O EvbayekhaInternal Medicine, St. Luke's Hospital, Chesterfield, USA.
Mohammad Z KhalilullahInternal Medicine, Brody School of Medicine at East Carolina University, Greenville, USA.
Olanrewaju K AdabaleInternal Medicine, Brody School of Medicine at East Carolina University, Greenville, USA.
Tracy-Ann PoyserInternal Medicine, Unity Health White County Medical Center, Searcy, USA.
Osejie F OriaifoInternal Medicine, Brody School of Medicine at East Carolina University, Greenville, USA.
Ufuoma I OloriInternal Medicine, Jersey City Medical Center, Jersey City, USA.
Henry O AiwuyoInternal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.
White Memorial Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening syndrome of excessive inflammation and tissue destruction secondary to abnormal immune activation. The term macrophage activation syndrome (MAS) is used when HLH develops in the setting of systemic juvenile idiopathic arthritis (SJIA; formerly known as Still's disease), adult-onset Still's disease, or any other rheumatologic disorder. We present a case of a 21-year-old female with a known history of SJIA who presented to the hospital with fever, chills, myalgia, nausea, vomiting, and hypotension. Initial evaluation at the time of presentation suggested sepsis likely due to acute pyelonephritis, and the patient was started on antibiotics and intravenous fluid hydration. However, further workup suggested that her symptoms were non-infectious and were likely due to MAS, a rare complication of SJIA. We promptly diagnosed her, and she received a course of steroids and made an uneventful recovery.

Indexed as

adult-onset still’s diseaseadult-onset still’s disease (aosd)hemophagocytic lymphohistiocytosishemophagocytic lymphohistiocytosis (hlh)macrophage activation syndromemacrophage activation syndrome (mas)sepsisuti

Identifiers

PMID37012949
PMCPMC10065992
OpenAlexW4322773056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.