Evidence map›Paper›PMID 37012909›Full record

ArticleHeliyon2023

Fabrication of bFGF/polydopamine-loaded PEEK implants for improving soft tissue integration by upregulating Wnt/β-catenin signaling.

Xiaohu Wang, Ning Ma, Li Feng, Mingkui Shen, Yaqi Zhou, Xinan Zhang, Ruichao Huang, Li Zhou, Shanfeng Ji, Yongli Lou and 1 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xiaohu WangDepartment of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Ning MaIntensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450001, China.
Li FengSchool of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.
Mingkui ShenSchool of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.
Yaqi ZhouDepartment of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Xinan ZhangDepartment of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Ruichao HuangDepartment of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Li ZhouDepartment of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Shanfeng JiDepartment of Neurosurgery, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Yongli LouDepartment of Neurosurgery, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Zhi ZhuDepartment of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Zhengzhou Central Hospital · CNSouthern University of Science and Technology · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The difficulties associated with polyetheretherketone (PEEK) implants and soft tissue integration for craniomaxillofacial bone repair have led to a series of complications that limit the clinical benefits. In this study, 3D printed multi-stage microporous PEEK implants coated with bFGF via polydopamine were fabricated to enhance PEEK implant-soft tissue integration. Multistage microporous PEEK scaffolds prepared by sulfonation of concentrated sulfuric acid were coated with polydopamine, and then used as templates for electrophoretic deposition of bFGF bioactive factors. Achieving polydopamine and bFGF sustained release, the composite PEEK scaffolds possessed good mechanical properties, hydrophilicity, protein adhesion properties. The

Indexed as

bFGFPolydopaminePolyetheretherketoneSoft tissue integrationWnt/β-catenin signaling

Identifiers

PMID37012909
PMCPMC10066536
OpenAlexW4328053556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.