Evidence map›Paper›PMID 37012452›Full record

ReviewArchives of microbiology2023

Cyanometabolites: molecules with immense antiviral potential.

Uma Singh, Harsh A Gandhi, Nikita, Jaydeep Bhattacharya, Ravi Tandon, G L Tiwari, Richa Tandon

Open access · bronzeAbstract readReview
In one paragraph

Review in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Effect of high-doseFrontiers in immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Uma SinghDepartment of Botany, University of Allahabad, Prayagraj, 211002, India.
Harsh A GandhiNanobiotechnology Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
NikitaLaboratory of AIDS Research and Immunology, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Jaydeep BhattacharyaNanobiotechnology Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Ravi TandonLaboratory of AIDS Research and Immunology, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
G L TiwariDepartment of Botany, University of Allahabad, Prayagraj, 211002, India.
Richa TandonDepartment of Botany, S. S. Khanna Girls Degree College, University of Allahabad, Prayagraj, 211003, India. drrichatandon@gmail.com.
Jawaharlal Nehru University · INUniversity of Allahabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanometabolites are active compounds derived from cyanobacteria that include small low molecular weight peptides, oligosaccharides, lectins, phenols, fatty acids, and alkaloids. Some of these compounds may pose a threat to human and environment. However, majority of them are known to have various health benefits with antiviral properties against pathogenic viruses including Human immunodeficiency virus (HIV), Ebola virus (EBOV), Herpes simplex virus (HSV), Influenza A virus (IAV) etc. Cyanometabolites classified as lectins include scytovirin (SVN), Oscillatoria agardhii agglutinin (OAAH), cyanovirin-N (CV-N), Microcystis viridis lectin (MVL), and microvirin (MVN) also possess a potent antiviral activity against viral diseases with unique properties to recognize different viral epitopes. Studies showed that a small linear peptide, microginin FR1, isolated from a water bloom of Microcystis species, inhibits angiotensin-converting enzyme (ACE), making it useful for the treatment of coronavirus disease 2019 (COVID-19). Our review provides an overview of the antiviral properties of cyanobacteria from the late 90s till now and emphasizes the significance of their metabolites in combating viral diseases, particularly severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has received limited attention in previous publications. The enormous medicinal potential of cyanobacteria is also emphasized in this review, which justifies their use as a dietary supplement to fend off pandemics in future.

Indexed as

COVID-19CyanobacteriaAntiviral AgentsHumansLectinsSARS-CoV-2Antiviral AgentsLectinsAntiviralCOVID-19CyanobacteriaCyano-metabolitesHIVMicrovirinScytovirin

Identifiers

PMID37012452
PMCPMC10069739
OpenAlexW4362521560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.