Evidence map›Paper›PMID 37012441›Full record

ReviewNature reviews. Urology2023

Unanswered questions in prostate cancer - findings of an international multi-stakeholder consensus by the PIONEER consortium.

Muhammad Imran Omar, Steven MacLennan, Maria J Ribal, Monique J Roobol, Konstantinos Dimitropoulos, Thomas van den Broeck, Sara J MacLennan, Susan Evans Axelsson, Giorgio Gandaglia, Peter-Paul Willemse and 9 more

Open access · bronzeAbstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 20 institutions in 10 countries.

Muhammad Imran OmarAcademic Urology Unit, University of Aberdeen, Aberdeen, UK. m.i.omar@abdn.ac.uk.ORCID 0000-0002-1597-3126
Steven MacLennanAcademic Urology Unit, University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-2691-8421
Maria J RibalGuidelines Office, European Association of Urology, Arnhem, Netherlands.
Monique J RoobolErasmus MC, Rotterdam, Netherlands.ORCID 0000-0001-6967-1708
Konstantinos DimitropoulosAcademic Urology Unit, University of Aberdeen, Aberdeen, UK.
Thomas van den BroeckGuidelines Office, European Association of Urology, Arnhem, Netherlands.
Sara J MacLennanAcademic Urology Unit, University of Aberdeen, Aberdeen, UK.ORCID 0000-0003-1405-6964
Susan Evans AxelssonBayer AG, Berlin, Germany.
Giorgio GandagliaDepartment of Urology and Division of Experimental Oncology, Urological Research Institute, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Peter-Paul WillemseGuidelines Office, European Association of Urology, Arnhem, Netherlands.
Ken MastrisEuropean Cancer Patient Coalition, Brussels, Belgium.
John Butler RansohoffBayer AG, Berlin, Germany.
Zsuzsanna DevecseriSanofi, Chilly-Mazarin, France.ORCID 0000-0001-7648-3633
Thomas AbbottAstellas, Leiden, Netherlands.
Bertrand De MeulderAssociation EISBM, Vourles, France.
Anders BjartellDepartment of Translational Medicine, Lund University, Lund, Sweden.
Alex AsiimweBayer AG, Berlin, Germany.
James N'DowAcademic Urology Unit, University of Aberdeen, Aberdeen, UK.
PIONEER Consortium
Bayer (Germany) · DEEuropean Association of Urology · NLAstellas Pharma (Netherlands) · NLAstraZeneca (United Kingdom) · GBOrion Corporation (Finland) · FIErasmus MC · NLEuropean Institute for Systems Biology and MedicineTampere University · FITechnische Universität Dresden · DEUniversity of Aberdeen · GBVita-Salute San Raffaele University · ITJanssen (Belgium) · BESwedish Institute for Health Economics · SEThe Hyve (Netherlands) · NLFraunhofer Institute for Cell Therapy and Immunology · DEHelmholtz Association of German Research Centres · DEImperial College London · GBIQVIA (United Kingdom) · GBUniversity of Gothenburg · SECovance (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PIONEER is a European network of excellence for big data in prostate cancer consisting of 37 private and public stakeholders from 9 countries across Europe. Many progresses have been done in prostate cancer management, but unanswered questions in the field still exist, and big data could help to answer these questions. The PIONEER consortium conducted a two-round modified Delphi survey aiming at building consensus between two stakeholder groups - health-care professionals and patients with prostate cancer - about the most important questions in the field of prostate cancer to be answered using big data. Respondents were asked to consider what would be the effect of answering the proposed questions on improving diagnosis and treatment outcomes for patients with prostate cancer and to score these questions on a scale of 1 (not important) to 9 (critically important). The mean percentage of participants who scored each of the proposed questions as critically important was calculated across the two stakeholder groups and used to rank the questions and identify the highest scoring questions in the critically important category. The identification of questions in prostate cancer that are important to various stakeholders will help the PIONEER consortium to provide answers to these questions to improve the clinical care of patients with prostate cancer.

Indexed as

Prostatic NeoplasmsEuropeHumansMaleTreatment Outcome

Identifiers

PMID37012441
OpenAlexW4362523725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.