Observational studyScientific reports2023
Impact of frailty on long-term mortality in older patients receiving intensive care via the emergency department.
Observational study in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
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Who cites it
11 citing papers in PubMed.
- Factors Associated with Invasive Mechanical Ventilation Requirement in Older ICU Patients: The Roles of Frailty, Comorbidity, and Acute Illness Severity.Biomedicines · 2026Article
- Impact of Legal Protection on Life-Support Interventions and 3-Month Mortality in the Intensive Care Unit: The Vulne-Rea Study.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Frailty in Critically Ill Cancer Patients in a Lower-middle Income Country-Prevalence, Risk Factors, and Impact on Acute Clinical Outcomes and Postdischarge Health-related Quality of Life: A Single Center Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Frailty and Outcomes in Elderly ICU Patients: Insights from a Portuguese Cohort.Healthcare (Basel, Switzerland) · 2025Article
- The Importance of Frailty in Determining Survival After Intensive Care.Journal of clinical medicine · 2025Article
- The pictorial fit-frail scale: a novel tool for frailty assessment in critically ill older adults.BMC geriatrics · 2025Article
- Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study.Annals of intensive care · 2025Article
- Article
- Critical illness-related corticosteroid insufficiency: latest pathophysiology and management guidelines.Acute and critical care · 2024Article
- Long-term, patient-centered, frailty-based outcomes of older critical illness survivors from the emergency department: a post hoc analysis of the LIFE Study.BMC geriatrics · 2024Observational
Corrections and comments
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Authors and funding
22 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate whether frailty was associated with 6-month mortality in older adults who were admitted to the intensive care unit (ICU) with an illness requiring emergency care. The investigation was a prospective, multi-center, observational study conducted among the ICUs of 17 participating hospitals. Patients ≥ 65 years of age who were admitted to the ICU directly from an emergency department visit were assessed to determine their baseline Clinical Frailty Scale (CFS) scores before the illness and were surveyed 6 months after admission. Among 650 patients included in the study, the median age was 79 years old, and overall mortality at 6 months was as low as 21%, ranging from 6.2% in patients with CFS 1 to 42.9% in patients with CFS ≥ 7. When adjusted for potential confounders, CFS score was an independent prognostic factor for mortality (one-point increase in CFS, adjusted risk ratio with 95% confidence interval 1.19 [1.09-1.30]). Quality of life 6 months after admission worsened as baseline CFS score increased. However, there was no association between total hospitalization cost and baseline CFS. CFS is an important predictor of long-term outcomes among critically ill older patients requiring emergent admission.
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