Evidence map›Paper›PMID 37012315›Full record

ArticleCommunications biology2023

Long-term depression in neurons involves temporal and ultra-structural dynamics of phosphatidylinositol-4,5-bisphosphate relying on PIP5K, PTEN and PLC.

Sarah A Hofbrucker-MacKenzie, Eric Seemann, Martin Westermann, Britta Qualmann, Michael M Kessels

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. MARCKS and PI(4,5)PMolecular biology of the cell · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah A Hofbrucker-MacKenzieInstitute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany.
Eric SeemannInstitute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany.ORCID 0000-0002-3270-1253
Martin WestermannCenter for Electron Microscopy, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany.
Britta QualmannInstitute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany. Britta.Qualmann@med.uni-jena.de.ORCID 0000-0002-5743-5764
Michael M KesselsInstitute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany. Michael.Kessels@med.uni-jena.de.ORCID 0000-0001-5967-0744
Jena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synaptic plasticity involves proper establishment and rearrangement of structural and functional microdomains. Yet, visualization of the underlying lipid cues proved challenging. Applying a combination of rapid cryofixation, membrane freeze-fracturing, immunogold labeling and electron microscopy, we visualize and quantitatively determine the changes and the distribution of phosphatidylinositol-4,5-bisphosphate (PIP

Indexed as

Long-Term Synaptic DepressionNeuronsPhosphatidylinositolsNeuronal PlasticityPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol 4,5-DiphosphatePhosphatidylinositols

Identifiers

PMID37012315
PMCPMC10070498
OpenAlexW4362523912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.