ArticleNature communications2023
In situ orderly self-assembly strategy affording NIR-II-J-aggregates for in vivo imaging and surgical navigation.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 94 citations in OpenAlex.
- Constructing a NIR AIEgen Based on the Novel Molecular Framework for Imaging Lipid Droplet Accumulation in Parkinson's Disease Mouse Brain.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- A head-to-tail dimeric J-aggregate probe for rapid and ratiometric imaging of mitochondrial 5-HTChemical science · 2026Article
- π-π-Coupled J-Aggregates Synergized With Hydrogen Bonding via Molecular Planarity Engineering for Second Near-Infrared Imaging and Phototherapy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Fluorescence Tuning of Carbon Dots from Red to Blue via UV-Induced Photochemical Etching.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- ROS-Activatable J‑Aggregate Formation of a NIR-II Fluorescent Sensor for Detecting and Imaging Oxidative Stress-Associated Diseases In Vivo.Chemical & biomedical imaging · 2026Article
- Controlled In Situ Self-Assembly for Pretargeted Tumor Theranostics via Bioorthogonal Activation.Advanced healthcare materials · 2026Article
- Fluorescent J‑Aggregates in the NIR-II Window: Unlocking Frontiers in Biomedical Imaging.Chemical & biomedical imaging · 2026Review
- Harnessing Supramolecular J-Aggregates in Deep Eutectic Solvents for Tunable NIR Photothermal and Photodynamic Therapy.Nano letters · 2026Article
- Directional conjugation of monoclonal antibodies to nanoparticles using metal-free click chemistry.Nature protocols · 2026Review
- Hypoxia-responsive self-assembled nanoparticles for reprogramming tumor-associated macrophages into an anti-tumor M1 phenotype in breast cancer.Materials today. Bio · 2026Article
- Architecting NIR-II metal supramolecular dyes-illuminating the path to precision medicine.Chemical science · 2026Review
- Two-dimensional NIR-II AIE nanotheranostic probes with ultralarge Stokes shifts for surgical navigation and ablation of glioma.Science advances · 2026Article
- Size-tuned PEGylated NIR-II fluorescent probes for high-contrast plant imaging and TMV detection.Journal of nanobiotechnology · 2025Article
- Near-infrared II cyanine fluorophores with large stokes shift engineered by regulating respective absorption and emission.Nature communications · 2025Article
- Long-term in vivo immune tracking nanoplatform based on AgBMC biology · 2025Article
- Aggregation control of anionic pentamethine cyanine enabling excitation wavelength selective NIR-II fluorescence imaging-guided photodynamic therapy.Nature communications · 2025Article
- SERS surgical navigation with postsurgical immunotherapy of local microtumors and distant metastases for improved anticancer outcomes.Science advances · 2024Article
- Supramolecular engineering cascade regulates NIR-II J-aggregates to improve photodynamic therapy.Chemical science · 2024Article
- Smart Molecular Imaging and Theranostic Probes by Enzymatic Molecular In Situ Self-Assembly.JACS Au · 2024Review
- Design strategies and biological applications of β-galactosidase fluorescent sensor in ovarian cancer research and beyond.RSC advances · 2024Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
J-aggregation, an effective strategy to extend wavelength, has been considered as a promising method for constructing NIR-II fluorophores. However, due to weak intermolecular interactions, conventional J-aggregates are easily decomposed into monomers in the biological environment. Although adding external carriers could help conventional J-aggregates stabilize, such methods still suffer from high-concentration dependence and are unsuitable for activatable probes design. Besides, these carriers-assisted nanoparticles are risky of disassembly in lipophilic environment. Herein, by fusing the precipitated dye (HPQ) which has orderly self-assembly structure, onto simple hemi-cyanine conjugated system, we construct a series of activatable, high-stability NIR-II-J-aggregates which overcome conventional J-aggregates carrier's dependence and could in situ self-assembly in vivo. Further, we employ the NIR-II-J-aggregates probe HPQ-Zzh-B to achieve the long-term in situ imaging of tumor and precise tumor resection by NIR-II imaging navigation for reducing lung metastasis. We believe this strategy will advance the development of controllable NIR-II-J-aggregates and precise bioimaging in vivo.
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