Evidence map›Paper›PMID 37011776›Full record

ReviewNeuroscience and biobehavioral reviews2023

Revisiting the focality of non-invasive brain stimulation - Implications for studies of human cognition.

Ole Numssen, Constantijn L van der Burght, Gesa Hartwigsen

Abstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Optimizing and assessing multichannel TMS focality.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Electric-field-based dosing for TMS.Imaging neuroscience (Cambridge, Mass.) · 2024
    Article
  12. Causal evidence for a coordinated temporal interplay within the language network.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ole NumssenLise Meitner Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Methods and Development Group Brain Networks, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. Electronic address: numssen@cbs.mpg.de.
Constantijn L van der BurghtPsychology of Language Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands.
Gesa HartwigsenLise Meitner Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Wilhelm Wundt Institute for Psychology, Leipzig University, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive brain stimulation techniques are popular tools to investigate brain function in health and disease. Although transcranial magnetic stimulation (TMS) is widely used in cognitive neuroscience research to probe causal structure-function relationships, studies often yield inconclusive results. To improve the effectiveness of TMS studies, we argue that the cognitive neuroscience community needs to revise the stimulation focality principle - the spatial resolution with which TMS can differentially stimulate cortical regions. In the motor domain, TMS can differentiate between cortical muscle representations of adjacent fingers. However, this high degree of spatial specificity cannot be obtained in all cortical regions due to the influences of cortical folding patterns on the TMS-induced electric field. The region-dependent focality of TMS should be assessed a priori to estimate the experimental feasibility. Post-hoc simulations allow modeling of the relationship between cortical stimulation exposure and behavioral modulation by integrating data across stimulation sites or subjects.

Indexed as

BrainTranscranial Magnetic StimulationCognitionHumansBrain stimulationCognitive neuroscienceField simulationNIBSTMS

Identifiers

PMID37011776
PMCPMC10186117

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.