ArticleObesity facts2023
Higher Risk of Sarcopenia in Older Adults with Type 2 Diabetes: NHANES 1999-2018.
Article in Obesity facts, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06337357 (Evaluating Resistance Training for Sarcopenia in Older Patients With Type 2 Diabetes), which is not on this map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating Resistance Training for Sarcopenia in Older Patients With Type 2 Diabetes: Treatment Outcomes
Who cites it
38 citing papers in PubMed, 57 citations in OpenAlex.
- Low-calorie, high-protein diets, regardless of protein source, improve glucose metabolism and cardiometabolic profiles in subjects with prediabetes or type 2 diabetes and overweight or obesity.Diabetes, obesity & metabolism · 2025Trial
- Association between bone microarchitecture and sarcopenia in postmenopausal women with type 2 diabetes.Archives of osteoporosis · 2024Trial
- Circulating biomarkers of the brain-muscle-metabolic axis in primary sarcopenia: neudesin, nesfatin-1, and irisin.European geriatric medicine · 2026Article
- Sarcopenia and Frailty in Type 2 Diabetes Mellitus: An Overlooked Challenge.Diabetes & metabolism journal · 2026Article
- Article
- Diabetes-related foot disease and sarcopenia-related traits: evidence from US and Chinese cohorts and mendelian randomization.Aging clinical and experimental research · 2026Article
- Effects of exercise training on frail older adults with heart failure: a systematic-review.Frontiers in aging · 2026Review
- Association between bone mineral content and sarcopenia in hospitalized patients with type 2 diabetes mellitus: a cross-sectional study.Frontiers in medicine · 2026Article
- TAS1R3 Regulates GTPase Signaling in Human Skeletal Muscle Cells for Glucose Uptake.International journal of molecular sciences · 2025Article
- Development and validation of a Four-Year predictive model for sarcopenia in older adults: insights from the CHARLS cohort.Aging clinical and experimental research · 2025Article
- Creatine Supplementation Combined with Exercise in the Prevention of Type 2 Diabetes: Effects on Insulin Resistance and Sarcopenia.Nutrients · 2025Review
- Sex‑specific effects of aging and glycemic control on the association of possible sarcopenia in older adults with type 2 diabetes: a cross-sectional study.Aging clinical and experimental research · 2025Article
- Observational
- Diabetes and Sarcopenia: Metabolomic Signature of Pathogenic Pathways and Targeted Therapies.International journal of molecular sciences · 2025Review
- Weight Gain, Weight Loss, and Type 2 Diabetes Risk: Evidence From the Atherosclerosis Risk in Communities (ARIC) Study.Endocrinology, diabetes & metabolism · 2025Article
- Association of Dietary Antioxidant Potential with Sarcopenia in Hypertension.Reviews in cardiovascular medicine · 2025Article
- Association between sarcopenia and the prevalence of gallstone in US adults: a cross-sectional analysis of NHANES.BMC gastroenterology · 2025Article
- Association between sarcopenia and weight-adjusted waist index in male patients with type 2 diabetes.BMC endocrine disorders · 2025Article
- Association between daily sitting time and sarcopenia in the US population: a cross-sectional study.Archives of public health = Archives belges de sante publique · 2025Article
- Association between neutrophil percentage-to-albumin ratio (NPAR) and sarcopenia in individuals with arthritis: a cross-sectional study.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRecent studies suggested that sarcopenia may be a significant comorbidity of diabetes mellitus (DM). Nonetheless, studies with nationally representative data are scarce, and the changing trend of sarcopenia prevalence over time is largely unknown. Therefore, we aimed to estimate and compare the prevalence of sarcopenia in diabetic and nondiabetic US older population, and to explore the potential predictors of sarcopenia as well as the trend of sarcopenia prevalent in the past decades.
methodsData were retrieved from the National Health and Nutrition Examination Survey (NHANES). Sarcopenia and DM were defined according to corresponding diagnosis criteria. Weighted prevalence was calculated and compared between diabetic and nondiabetic participants. The differences among age and ethnicity groups were explored.
resultsA total of 6,381 US adults (>50 years) were involved. The overall prevalence of sarcopenia was 17.8% for US elders, and the prevalence was higher (27.9% vs. 15.7%) in those with diabetes ones than those without. Stepwise regression revealed that sarcopenia was significantly associated with DM (adjusted odds ratio = 1.37, 95% CI: 1.08-1.22; p < 0.05) after controlling for potential confounders including gender, age, ethnicity, educational level, BMI, and muscle strengthening activity. A slight fluctuation but overall increasing trend of sarcopenia prevalence was observed among diabetic elders, while no obvious changing trend was observed in their counterparts in recent decades.
conclusionDiabetic US older adults face significantly higher risk of sarcopenia when compared with their nondiabetic counterparts. Gender, age, ethnicity, educational level, and obesity were important influencing factors of sarcopenia development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.