ArticleAnnals of internal medicine2023
Incremental Health Care Costs of Self-Reported Functional Impairments and Phenotypic Frailty in Community-Dwelling Older Adults : A Prospective Cohort Study.
Article in Annals of internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cost of illness analysis of frailty for older adults: a systematic review and meta-analysis.European geriatric medicine · 2025Pooled it
- Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial.Health technology assessment (Winchester, England) · 2026Trial
- Long-term frailty and physical performance transitions in older people with type-2 diabetes. The MIDFRAIL randomized clinical study.The journal of nutrition, health & aging · 2025Trial
- Loss of Independence Among Racially and Ethnically Diverse Older Adults: An ICF-Based Analysis of NHATS.Healthcare (Basel, Switzerland) · 2026Article
- Medicare costs and home time loss among fee-for-service beneficiaries by frailty and dementia status.The Journal of frailty & aging · 2026Article
- The association of frailty with health care costs using the FRAIL scale.Aging clinical and experimental research · 2026Article
- Using Indoor Movement Complexity in Smart Homes to Detect Frailty in Older Adults: Multiple-Methods Case Series Study.JMIR aging · 2026Article
- Modeled Health and Economic Burden of Frailty and Falls Among Adults With HIV.JAMA network open · 2026Article
- Losses to Follow-Up in a Nationally Representative Study of Community-Living Older Americans: Two Approaches to Censoring and Implications for Mortality Outcomes.Journal of the American Geriatrics Society · 2026Article
- Socioeconomic status and the relationship of physical performance with activities of daily living among US older adults.PloS one · 2026Article
- Article
- Additional hospitalization costs associated with delirium among older adults: evidence from the Medicare Current Beneficiary Survey.Frontiers in public health · 2026Article
- Effects of Functional Impairments and Frailty on the Association of Cognitive Impairment with Total Healthcare Costs: A Prospective Multi-cohort Study.Journal of general internal medicine · 2025Article
- Cognitive Frailty and Health Care Utilization and Costs Among Middle-Aged and Older Adults: Findings from Four Longitudinal Cohort Studies.Aging and disease · 2025Article
- Incremental Healthcare Costs of Dementia and Cognitive Impairment in Community-Dwelling Older Adults: A Prospective Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Identifying modifiable factors and their joint effect on frailty: a large population-based prospective cohort study.GeroScience · 2025Article
- Incremental healthcare costs of the simple SOF measure of phenotypic frailty in community-dwelling older adults.Journal of the American Geriatrics Society · 2025Article
- Neighborhood Socioeconomic Deprivation and Health Care Costs in Older Community-Dwelling Adults: Importance of Functional Impairment and Frailty.Journal of general internal medicine · 2024Article
- Functional Impairments, Phenotypic Frailty, and Sector-Specific Incremental Healthcare Costs in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundHealth care systems need better strategies to identify older adults at risk for costly care to select target populations for interventions to reduce health care burden.
objectiveTo determine whether self-reported functional impairments and phenotypic frailty are associated with incremental health care costs after accounting for claims-based predictors.
designProspective cohort study.
settingIndex examinations (2002 to 2011) of 4 prospective cohort studies linked with Medicare claims.
participants8165 community-dwelling fee-for-service beneficiaries (4318 women, 3847 men). MEASUREMENTS: Weighted (Centers for Medicare & Medicaid Services Hierarchical Condition Category index) and unweighted (count of conditions) multimorbidity and frailty indicators derived from claims. Self-reported functional impairments (difficulty performing 4 activities of daily living) and frailty phenotype (operationalized using 5 components) derived from cohort data. Health care costs ascertained for 36 months after index examinations.
resultsAverage annualized costs (2020 U.S. dollars) were $13 906 among women and $14 598 among men. After accounting for claims-based indicators, average incremental costs of functional impairments versus no impairment in women (men) were $3328 ($2354) for 1 impairment increasing to $7330 ($11 760) for 4 impairments; average incremental costs of phenotypic frailty versus robust in women (men) were $8532 ($6172). Mean predicted costs adjusted for claims-based indicators in women (men) varied by both functional impairments and the frailty phenotype ranging from $8124 ($11 831) among robust persons without impairments to $18 792 ($24 713) among frail persons with 4 impairments. Compared with the model with claims-derived indicators alone, this model resulted in more accurate cost prediction for persons with multiple impairments or phenotypic frailty. LIMITATION: Cost data limited to participants enrolled in the Medicare fee-for-service program.
conclusionSelf-reported functional impairments and phenotypic frailty are associated with higher subsequent health care expenditures in community-dwelling beneficiaries after accounting for several claims-based indicators of costs. PRIMARY FUNDING SOURCE: National Institutes of Health.
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