ArticlePlant physiology2023
The transcription factor PbrMYB24 regulates lignin and cellulose biosynthesis in stone cells of pear fruits.
Article in Plant physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 77 citations in OpenAlex.
- PbSnRK1-Mediated Phosphorylation of PbTCP13 Regulates Glucose-Responsive Lignin Biosynthesis via PbMYB11 During Pear Stone Cell Formation.Plant biotechnology journal · 2026Article
- The Dual Role of Lignin in Fruit Trees: Unraveling Regulatory Networks from Stress Resilience to Quality Control.Plants (Basel, Switzerland) · 2026Review
- Brassinosteroid signaling promotes stone cell lignification by enhancing nuclear accumulation of PbrBEH3 in pear fruit.The Plant journal : for cell and molecular biology · 2026Article
- ARF6 integrates auxin and gibberellin signaling to promote stone cell lignification in pear via the HB49-MYB169 module.The New phytologist · 2026Article
- Genome-Wide Analysis of the Cinnamoyl-CoA Reductase (CCR) Gene Family and Its Involvement in Lignin Biosynthesis and Stress Responses in Six Tea Plant Cultivars.International journal of molecular sciences · 2026Article
- Integrative transcriptome-metabolome dissection of the molecular basis of lodging resistance in oat (Avena sativa L.) basal internodes.BMC plant biology · 2026Article
- Mediator subunit MED25 represses ABI5-dependent activation of erucic acid biosynthetic geneFrontiers in plant science · 2026Article
- The PbrMADS1-PbrMYB169 complex has uniquely emerged to regulate lignification of stone cells in pear.Journal of integrative plant biology · 2026Article
- The MabZIP5-MaMYB69 module cooperates with MaERF55 to modulate banana fruit ripening via cell wall degradation.Horticulture research · 2026Article
- Exploring the molecular landscape of environmental responses in the Antarctic plantFrontiers in plant science · 2026Article
- Genomic insights into deleterious mutations and their impact on agronomic traits during pear domestication.Horticulture research · 2025Article
- CaHorticulture research · 2025Article
- Nitrate Modulates Fruit Lignification by RegulatingInternational journal of molecular sciences · 2025Article
- Gap-free genome assemblies of two Pyrus bretschneideri cultivars and GWAS analyses identify a CCCH zinc finger protein as a key regulator of stone cell formation in pear fruit.Plant communications · 2025Article
- Article
- Effects of different rehydration temperatures on rehydration and nutritional quality of dried daylily.PeerJ · 2025Article
- Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylpropanoid biosynthesis pathways under cold stress in Artemisia annua.Scientific reports · 2024Article
- Unveiling Key Genes and Unique Transcription Factors Involved in Secondary Cell Wall Formation inInternational journal of molecular sciences · 2024Article
- Ultrasound as a Physical Elicitor to Improve Texture in Blueberry Fruit: Physiological Indicator and Transcriptomic Analysis.Foods (Basel, Switzerland) · 2024Article
- Genome-wide investigation of glycoside hydrolase 9 (GH9) gene family unveils implications in orchestrating the mastication trait of Citrus sinensis fruits.BMC genomics · 2024Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Lignified stone cell content is a key factor used to evaluate fruit quality, influencing the economic value of pear (Pyrus pyrifolia) fruits. However, our understanding of the regulatory networks of stone cell formation is limited due to the complex secondary metabolic pathway. In this study, we used a combination of co-expression network analysis, gene expression profiles, and transcriptome analysis in different pear cultivars with varied stone cell content to identify a hub MYB gene, PbrMYB24. The relative expression of PbrMYB24 in fruit flesh was significantly correlated with the contents of stone cells, lignin, and cellulose. We then verified the function of PbrMYB24 in regulating lignin and cellulose formation via genetic transformation in homologous and heterologous systems. We constructed a high-efficiency verification system for lignin and cellulose biosynthesis genes in pear callus. PbrMYB24 transcriptionally activated multiple target genes involved in stone cell formation. On the one hand, PbrMYB24 activated the transcription of lignin and cellulose biosynthesis genes by binding to different cis-elements [AC-I (ACCTACC) element, AC-II (ACCAACC) element and MYB-binding sites (MBS)]. On the other hand, PbrMYB24 bound directly to the promoters of PbrMYB169 and NAC STONE CELL PROMOTING FACTOR (PbrNSC), activating the gene expression. Moreover, both PbrMYB169 and PbrNSC activated the promoter of PbrMYB24, enhancing gene expression. This study improves our understanding of lignin and cellulose synthesis regulation in pear fruits through identifying a regulator and establishing a regulatory network. This knowledge will be useful for reducing the stone cell content in pears via molecular breeding.
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