Evidence map›Paper›PMID 37011128›Full record

ArticlePLoS neglected tropical diseases2023

Hierarchical spatiotemporal modeling of human visceral leishmaniasis in Rio Grande do Norte, Brazil.

Helin G Hernandez, Grant D Brown, Iraci D Lima, José F Coutinho, Mary E Wilson, Eliana L T Nascimento, Selma M B Jeronimo, Christine A Petersen, Jacob J Oleson

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Visceral leishmaniasis risk clusters on Brazil's borders: 2013 to 2022.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Helin G HernandezDepartment of Biostatistics, University of Iowa, Iowa City, Iowa, United States of America.ORCID 0000-0001-9723-5954
Grant D BrownDepartment of Biostatistics, University of Iowa, Iowa City, Iowa, United States of America.
Iraci D LimaState Health Secretariat, State Government of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
José F CoutinhoInstitute of Tropical Medicine of Rio Grande do Norte, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Mary E WilsonDepartments of Internal Medicine and Microbiology & Immunology, University of Iowa, Iowa City, Iowa, United States of America.
Eliana L T NascimentoInstitute of Tropical Medicine of Rio Grande do Norte, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Selma M B JeronimoInstitute of Tropical Medicine of Rio Grande do Norte, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Christine A PetersenDepartment of Epidemiology, University of Iowa, Iowa City, Iowa, United States of America.
Jacob J OlesonDepartment of Biostatistics, University of Iowa, Iowa City, Iowa, United States of America.
University of Iowa · USUniversidade Federal do Rio Grande do Norte · BRGoverno do Estado do Rio Grande do Sul · BR

Funding

Alteration of skin immune environment by sand fly saliva across progressive LeishmaniasisR01AI171971 · NIAID · UNIVERSITY OF IOWA · PI Christine A Petersen · 2022 to 2026
$3.0M
Epidemic modeling framework for complex, multi-species disease processesR01TW010500 · FIC · UNIVERSITY OF IOWA · PI OLESON, JACOB, PETERSEN, CHRISTINE A · 2016 to 2020
$2.4M
BLRD VA I01 BX000536BLRD VA I01 BX001983FIC NIH HHS R01 TW010500NIAID NIH HHS R01 AI171971
6 · The paper itself

Abstract

Visceral leishmaniasis (VL) is a neglected tropical disease that is globally distributed and has the potential to cause very serious illness. Prior literature highlights the emergence and spread of VL is influenced by multiple factors, such as socioeconomic status, sanitation levels or animal and human reservoirs. The study aimed to retrospectively investigate the presence and infectiousness of VL in Rio Grande do Norte (RN), Brazil between 2007 and 2020. We applied a hierarchical Bayesian approach to estimate municipality-specific relative risk of VL across space and time. The results show evidence that lower socioeconomic status is connected to higher municipality-specific VL risk. Overall, estimates reveal spatially heterogeneous VL risks in RN, with a high probability that VL risk for municipalities within the West Potiguar mesoregion are more than double the expected VL risk. Additionally, given the data available, results indicate there is a high probability of increasing VL risk in the municipalities of Natal, Patu and Pau dos Ferros. These findings demonstrate opportunities for municipality-specific public health policy interventions and warrant future research on identifying epidemiological drivers in at-risk regions.

Indexed as

Leishmaniasis, VisceralAnimalsBayes TheoremBrazilCitiesHumansNeglected DiseasesRetrospective Studies

Identifiers

PMID37011128
PMCPMC10101641
OpenAlexW4362522170

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.