ArticleJournal of proteome research2023
High-Throughput Venomics.
Article in Journal of proteome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
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Who cites it
21 citing papers in PubMed.
- Article
- Harnessing prokaryotic amino acid transporters for metabolic engineering: mechanisms and biotechnological applications.Synthetic and systems biotechnology · 2026Review
- Profiling cytotoxicity of nanofractionated elapid snake venoms in human cell lines representing different tissues.Journal of pharmaceutical analysis · 2026Article
- Article
- Review
- Categorization and Characterization of Snake Venom Variability through Intact Toxin Analysis by Mass Spectrometry.Journal of proteome research · 2025Article
- Review
- Article
- Comparative Analysis of Tentacle Extract and Nematocyst Venom: Toxicity, Mechanism, and Potential Intervention in the Giant JellyfishMarine drugs · 2024Article
- Review
- Development of a membrane-disruption assay using phospholipid vesicles as a proxy for the detection of cellular membrane degradation.Toxicon: X · 2024Article
- Article
- Venom diversity in Naja mossambica: Insights from proteomic and immunochemical analyses reveal intraspecific differences.PLoS neglected tropical diseases · 2024Article
- High throughput identification of human monoclonal antibodies and heavy-chain-only antibodies to treat snakebite.Toxicon: X · 2024Article
- Recent advances in the exploration and discovery of SARS-CoV-2 inhibitory peptides from edible animal proteins.Frontiers in nutrition · 2024Review
- A Review of Rattlesnake Venoms.Toxins · 2023Review
- Acetylcholine-Binding Protein Affinity Profiling of Neurotoxins in Snake Venoms with Parallel Toxin Identification.International journal of molecular sciences · 2023Article
- An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules.Biochemical pharmacology · 2023Article
- Article
- Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms.PLoS neglected tropical diseases · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
In this study, we present high-throughput (HT) venomics, a novel analytical strategy capable of performing a full proteomic analysis of a snake venom within 3 days. This methodology comprises a combination of RP-HPLC-nanofractionation analytics, mass spectrometry analysis, automated in-solution tryptic digestion, and high-throughput proteomics. In-house written scripts were developed to process all the obtained proteomics data by first compiling all Mascot search results for a single venom into a single Excel sheet. Then, a second script plots each of the identified toxins in so-called Protein Score Chromatograms (PSCs). For this, for each toxin, identified protein scores are plotted on the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.