Evidence map›Paper›PMID 37010224›Full record

ArticlePsychological medicine2023

Impaired self-awareness of cognitive deficits in Parkinson's disease relates to cingulate cortex dysfunction.

Franziska Maier, Andrea Greuel, Marius Hoock, Rajbir Kaur, Masoud Tahmasian, Frank Schwartz, Ilona Csoti, Frank Jessen, Alexander Drzezga, Thilo van Eimeren and 2 more

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In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Beyond motor: a systematic review of multisensory integration deficits in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
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  11. Combined brain topological metrics with machine learning to distinguish essential tremor and tremor-dominant Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Franziska MaierDepartment of Psychiatry and Psychotherapy, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
Andrea GreuelDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.ORCID 0000-0002-0001-9225
Marius HoockDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.
Rajbir KaurDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.
Masoud TahmasianInstitute of Medical Science and Technology, Shahid Beheshti University, Tehran, Iran.
Frank SchwartzDepartment of Neurology, Hospital of the Brothers of Mercy, Trier, Germany.
Ilona CsotiGertrudis Clinic, Parkinson-Center, Leun-Biskirchen, Germany.
Frank JessenDepartment of Psychiatry and Psychotherapy, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
Alexander DrzezgaGerman Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.
Thilo van EimerenCognitive Neuroscience, Institute of Neuroscience and Medicine (INM-2), Research Center Jülich, Jülich, Germany.
Lars TimmermannDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.
Carsten EggersDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImpaired self-awareness of cognitive deficits (ISAcog) has rarely been investigated in Parkinson's disease (PD). ISAcog is associated with poorer long-term outcome in other diseases. This study examines ISAcog in PD with and without mild cognitive impairment (PD-MCI), compared to healthy controls, and its clinical-behavioral and neuroimaging correlates.

methodsWe examined 63 PD patients and 30 age- and education-matched healthy controls. Cognitive state was examined following the Movement Disorder Society Level II criteria. ISAcog was determined by subtracting

resultsPD-MCI patients (

conclusionsSimilar to Alzheimer's disease, the cingulate cortex seems to be relevant in ISAcog in PD. In PD-MCI patients, ISAcog might result from a disrupted network that regulates awareness of cognition and error processes.

Indexed as

Cognitive DysfunctionParkinson DiseaseBrainCognitionFluorodeoxyglucose F18GlucoseGyrus CinguliHumansMagnetic Resonance ImagingTomography, X-Ray ComputedFluorodeoxyglucose F18GlucoseAnosognosiaimpaired self-awarenessmild cognitive impairmentmultimodal neuroimagingParkinson's disease

Identifiers

PMID37010224
PMCPMC10009405

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.