ArticlePsychological medicine2023
Social engagement and allostatic load mediate between adverse childhood experiences and multimorbidity in mid to late adulthood: the Canadian Longitudinal Study on Aging.
Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Childhood violence exposure and externalizing behaviors: A systematic review of the role of physiological biomarkers.Psychoneuroendocrinology · 2022Pooled it
- Navigating Adversity in Older Age: An Integrative Review of Contemporary Resilience Concepts and Measurement Challenges.Geriatrics (Basel, Switzerland) · 2026Review
- Adverse Childhood Experiences, Pregnancy and Postpartum Depressive Symptoms, and Child Socioemotional Problems Over the First Three Years of Life.Child maltreatment · 2026Article
- Exploring the association between common genetic deletions and aging: insights from the Canadian Longitudinal Study on Aging.GeroScience · 2026Article
- Stress, Well-Being, and Reproduction in Wildlife.Advances in experimental medicine and biology · 2026Review
- Allostatic load profiles, resilience, and psychosocial adaptation in young adults.Frontiers in psychology · 2026Article
- Article
- Adverse Life Events Across the Life Course and the Risk of New-Onset Cardiovascular-Kidney-Metabolic Multimorbidity in Middle-Aged and Older Adults: Longitudinal Evidence From CHARLS.Journal of the American Heart Association · 2025Article
- Disparities in Allostatic Load Among Different Races: A Comprehensive Scoping Review.Journal of racial and ethnic health disparities · 2025Review
- The impact of early childhood adversity on adult cognitive performance: The mediating roles of childhood cognitive ability and educational attainment.Social science & medicine (1982) · 2025Article
- Adverse Childhood Experiences and the Co-occurrence of Poor Oral Health and Multimorbidity: Findings From the Canadian Longitudinal Study on Aging.Community dentistry and oral epidemiology · 2025Article
- Allostatic Interoceptive Overload Across Psychiatric and Neurological Conditions.Biological psychiatry · 2025Review
- Adverse childhood experiences and perceived body size across the life course: a longitudinal study using data from the Canadian Longitudinal Study on Aging (CLSA).BMJ public health · 2025Article
- Allostasis, health, and development in Latin America.Neuroscience and biobehavioral reviews · 2024Review
- The Longitudinal Dyadic Associations Between Social Participation and Cognitive Function in Older Chinese Couples.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- The gender and age perspectives of allostatic load.Frontiers in medicine · 2024Review
- Profiles of childhood adversities in Inuit from Nunavik: description and associations with indicators of socioeconomic characteristics, support, and community involvement.Canadian journal of public health = Revue canadienne de sante publique · 2024Article
- Childhood health and educational disadvantage are associated with adult multimorbidity in the global south: findings from a cross-sectional analysis of nationally representative surveys in India and Brazil.Journal of epidemiology and community health · 2023Article
- A longitudinal study evaluating adverse childhood experiences and obesity in adulthood using the Canadian Longitudinal Study on Aging (CLSA).International journal of epidemiology · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
backgroundAdverse childhood experiences (ACEs) are associated with multimorbidity in adulthood. This link may be mediated by psychosocial and biological factors, but evidence is lacking. The current study evaluates this mediation model.
methodWe analyzed data from the Canadian Longitudinal Study of Aging (
resultsIn the overall sample, ACEs were associated with multimorbidity, directly,
conclusionsACEs are related to multimorbidity, directly and via social engagement and allostatic load. This is the first study to show mediated pathways between early adversity and multimorbidity in adulthood. It provides a platform for understanding multimorbidity as a lifespan dynamic informing the co-occurrence of the varied disease processes represented in multimorbidity.
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