Evidence map›Paper›PMID 37010212›Full record

ArticlePsychological medicine2023

Antidepressant use in low- middle- and high-income countries: a World Mental Health Surveys report.

Alan E Kazdin, Chi-Shin Wu, Irving Hwang, Victor Puac-Polanco, Nancy A Sampson, Ali Al-Hamzawi, Jordi Alonso, Laura Helena Andrade, Corina Benjet, José-Miguel Caldas-de-Almeida and 22 more

Abstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prevalence of antidepressant use in Brazil: a systematic review with meta-analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2024
    Pooled it
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  19. Navigating the Intersection of Technology and Depression Precision Medicine.Advances in experimental medicine and biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Alan E KazdinDepartment of Psychology, Yale University, New Haven, CT, USA.ORCID 0000-0003-2319-9473
Chi-Shin WuDepartment of Psychiatry, National Taiwan University Hospital & College of Medicine, Taipei, Taiwan.
Irving HwangDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Victor Puac-PolancoDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Ali Al-HamzawiCollege of Medicine, Al-Qadisiya University, Diwaniya governorate, Al Diwaniyah, Iraq.
Jordi AlonsoHealth Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain.
Laura Helena AndradeNúcleo de Epidemiologia Psiquiátrica - LIM 23, Instituto de Psiquiatria Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Corina BenjetDepartment of Epidemiologic and Psychosocial Research, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico.
José-Miguel Caldas-de-AlmeidaLisbon Institute of Global Mental Health and Chronic Diseases Research Center (CEDOC), NOVA Medical School | Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
Giovanni de GirolamoIRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
Peter de JongeDepartment of Developmental Psychology, University of Groningen, Groningen, The Netherlands.
Silvia FlorescuNational School of Public Health, Management and Development, Bucharest, Romania.
Oye GurejeDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
Josep M HaroParc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Sant Boi de Llobregat, Barcelona, Spain.
Meredith G HarrisSchool of Public Health, The University of Queensland, Herston, QLD 4006, Australia.
Elie G KaramFaculty of Medicine, Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Balamand University, Beirut, Lebanon.
Georges KaramFaculty of Medicine, Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Balamand University, Beirut, Lebanon.
Viviane Kovess-MasfetyEcole des Hautes Etudes en Santé Publique (EHESP), EA 4057, Paris Descartes University, Paris, France.
Sing LeeDepartment of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong.
John J McGrathQueensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol QLD 4072, Australia.
Fernando Navarro-MateuUDIF-SM, Servicio Murciano de Salud; IMIB-Arrixaca; CIBERESP-Murcia, Región de Murcia, Spain.
Daisuke NishiDepartment of Mental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Bibilola D OladejiDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
José Posada-VillaColegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia.
Dan J SteinDepartment of Psychiatry & Mental Health and South African Medical Council Research Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa.
T Bedirhan ÜstünDepartment of Psychiatry, Koç University, Istanbul, Turkey.
Daniel V VigoDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
Zahari ZarkovDepartment of Mental Health, National Center of Public Health and Analyses, Sofia, Bulgaria.
Alan M ZaslavskyDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4831-2305
WHO World Mental Health Survey collaborators

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481NIDA NIH HHS R01 DA016558NIMH NIH HHS R01 MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R13 MH066849NIMH NIH HHS U01 MH060220
6 · The paper itself

Abstract

backgroundThe most common treatment for major depressive disorder (MDD) is antidepressant medication (ADM). Results are reported on frequency of ADM use, reasons for use, and perceived effectiveness of use in general population surveys across 20 countries.

methodsFace-to-face interviews with community samples totaling

results3.1% of respondents reported ADM use within the past 12 months. In high-income countries (HICs), depression (49.2%) and anxiety (36.4%) were the most common reasons for use. In low- and middle-income countries (LMICs), depression (38.4%) and sleep problems (31.9%) were the most common reasons for use. Prevalence of use was 2-4 times as high in HICs as LMICs across all examined diagnoses. Newer ADMs were proportionally used more often in HICs than LMICs. Across all conditions, ADMs were reported as

conclusionADMs are in widespread use and for a variety of conditions including but going beyond depression and anxiety. In a general population sample from multiple LMICs and HICs, ADMs were widely perceived to be either very or somewhat effective by the people who use them.

Indexed as

Major Depressive DisorderAntidepressive AgentsDeveloped CountriesDeveloping CountriesHealth SurveysHumansSurveys and QuestionnairesAntidepressive AgentsAntidepressant medicationsperceived effectivenessreasons for use

Identifiers

PMID37010212
PMCPMC10071359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.