ReviewJournal of magnetic resonance imaging : JMRI2023
Updates on Compositional MRI Mapping of the Cartilage: Emerging Techniques and Applications.
Review in Journal of magnetic resonance imaging : JMRI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Spatial Investigation of Facet Joint Cartilage Properties Reveals Specific Structure-Function Relationships.JOR spine · 2026Article
- Correlation between functional impairment and quantitative MRI assessment of ankle cartilage in chronic ankle instability.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2026Article
- Association of patellofemoral malalignment with early trochlear and patellar chondromalacia: a prospective T2* mapping study.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- Electroacupuncture for knee osteoarthritis: a multicentre randomised controlled trial assessing symptomatic and structural efficacy.EClinicalMedicine · 2026Article
- Detection of Early Knee Osteoarthritis Using Multi-Component TJournal of magnetic resonance imaging : JMRI · 2026Article
- A memory based model for cartilage and meniscus segmentation in 3D knee MRI.Scientific reports · 2025Article
- A Multidimensional Definition of Pre-Osteoarthritis: Toward 21st-Century Subclinical Detection and Targeted Intervention.International journal of molecular sciences · 2025Review
- CORR Insights®: Does Valgus Bracing Reduce Estimates of Medial Tibial, Medial Femoral, and Patella Cartilage Contact Pressure in Varus Malaligned Medial Knee Osteoarthritis?Clinical orthopaedics and related research · 2025Article
- [EJNMMI research · 2025Article
- HSGDNet: Hybrid Synthetic-Data-Guided Deep Learning With NLS Refinement for Fast Multi-Component T1ρ Knee Mapping.NMR in biomedicine · 2025Article
- Magnetic resonance imaging of cruciate ligament disorders: current updates.EFORT open reviews · 2025Review
- Transformative approaches for effective clinical trials to reduce the disease burden of osteoarthritis.Seminars in arthritis and rheumatism · 2025Review
- Beyond the Surface: Nutritional Interventions Integrated with Diagnostic Imaging Tools to Target and Preserve Cartilage Integrity: A Narrative Review.Biomedicines · 2025Review
- Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths.Heliyon · 2025Article
- Commentary: Efficacy and safety of low-molecular-weight collagen peptides in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial.Frontiers in nutrition · 2025Article
- MRI monitoring of USPIO-labeled BMSCs combined with alginate scaffold for cartilage defect repair.Frontiers in bioengineering and biotechnology · 2025Article
- MRI assessment of autologous osteochondral transplantation in talus: correlation with clinical outcomes and second look.Frontiers in sports and active living · 2025Article
- Quantitative MRI methods for the assessment of structure, composition, and function of musculoskeletal tissues in basic research and preclinical applications.Magma (New York, N.Y.) · 2024Review
- Gaining Insight into Updated MR Imaging for Quantitative Assessment of Cartilage Injury in Knee Osteoarthritis.Current rheumatology reports · 2024Review
- Cartilage compositional MRI-a narrative review of technical development and clinical applications over the past three decades.Skeletal radiology · 2024Review
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Authors and funding
6 authors.
Funding
Abstract
Osteoarthritis (OA) is a widely occurring degenerative joint disease that is severely debilitating and causes significant socioeconomic burdens to society. Magnetic resonance imaging (MRI) is the preferred imaging modality for the morphological evaluation of cartilage due to its excellent soft tissue contrast and high spatial resolution. However, its utilization typically involves subjective qualitative assessment of cartilage. Compositional MRI, which refers to the quantitative characterization of cartilage using a variety of MRI methods, can provide important information regarding underlying compositional and ultrastructural changes that occur during early OA. Cartilage compositional MRI could serve as early imaging biomarkers for the objective evaluation of cartilage and help drive diagnostics, disease characterization, and response to novel therapies. This review will summarize current and ongoing state-of-the-art cartilage compositional MRI techniques and highlight emerging methods for cartilage compositional MRI including MR fingerprinting, compressed sensing, multiexponential relaxometry, improved and robust radio-frequency pulse sequences, and deep learning-based acquisition, reconstruction, and segmentation. The review will also briefly discuss the current challenges and future directions for adopting these emerging cartilage compositional MRI techniques for use in clinical practice and translational OA research studies. EVIDENCE LEVEL: 2 TECHNICAL EFFICACY: Stage 2.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.