ArticleLangenbeck's archives of surgery2023
The diagnostic value of the systemic immune-inflammatory index in acute appendicitis cases in the emergency department.
Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Systemic Inflammatory Indices and Disease Severity in Acute Colonic Pseudo-Obstruction: An Exploratory Retrospective Study.Diagnostics (Basel, Switzerland) · 2026Article
- Comparative evaluation of the diagnostic value of HALP Score and systemic inflammatory immune index biomarkers in childhood appendicitis.Pakistan journal of medical sciences · 2025Article
- The Role of Systemic Immune-Inflammation Index (SII) in Diagnosing Pediatric Acute Appendicitis.Diagnostics (Basel, Switzerland) · 2025Article
- Diagnosing acute appendicitis in children with neutrophil-lymphocyte ratio: a cross-sectional study.Frontiers in pediatrics · 2025Article
- Diagnostic Value of Systemic Immune Inflammation Index in Identifying Complicated Acute Appendicitis Cases.Cureus · 2024Article
- Evaluating the prognostic value of systemic immune-inflammatory index in patients with acute decompensated heart failure.ESC heart failure · 2024Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimAcute appendicitis (AA) is one of the most common causes of acute abdomen conditions and continues to cause mortality and morbidity despite all the improvements. There is still a necessity for inexpensive and easily calculable index and scoring systems with fewer side effects for the diagnosis of AA and the detection of complications. Since the systemic immune-inflammation index (SIII) is an index that could be used in this context, we aimed to measure the success and reliability of SIII for the diagnosis of AA and related complications and to contribute to the literature.
methodsOur study was carried out retrospectively in a tertiary care hospital and conducted with 180 AA patients (study group-SG) and 180 control group (CG) patients. Demographic data, laboratory data, and clinical data of the cases, as well as the Alvarado score (AS), adult appendicitis score (AAS), and SIII and neutrophil/lymphocyte ratio (NLR) values calculated from laboratory data, were recorded in the previously created study form. p<0.05 was accepted as the significance level for the study.
resultsIn this study, age and gender were similar in the SG and CG groups. SIII and NLR levels calculated in SG cases were found to be significantly higher than CG. In addition, SIII and NLR levels were found to be significantly higher in complicated AA cases than in complicated cases. Although SIII was more significant in the diagnosis of AA, NLR was more successful than SIII in detecting the presence of complications. SIII, NLR, AAS, and AS were significantly positively correlated in the diagnosis of AA. In the presence of peritonitis, SIII and NLR were also found to be significantly higher when compared to cases without peritonitis.
conclusionsWe found that SIII is a usable index in the diagnosis of AA and the prediction of complicated AA. However, NLR was found to be more significant than SIII in estimating complicated AA. In addition, it is recommended to be careful in terms of peritonitis in cases with high SIII and NLR levels.
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