Evidence map›Paper›PMID 37009881›Full record

ArticleEpidemiology and infection2023

Hepatitis B in Africa Collaborative Network: cohort profile and analysis of baseline data.

Nicholas Riches, Michael Vinikoor, Alice Guingane, Asgeir Johannessen, Maud Lemoine, Philippa Matthews, Edith Okeke, Yusuke Shimakawa, Roger Sombie, Alexander Stockdale and 13 more

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Customizable Data Quality Tool for Global Observational Research Networks.Studies in health technology and informatics · 2025
    Article
  5. Global elimination of HBV: Is it really achievable?Journal of viral hepatitis · 2024
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 10 countries.

Nicholas RichesDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.ORCID 0000-0002-1729-7635
Michael VinikoorDepartment of Internal Medicine, University of Zambia, Lusaka, Zambia.
Alice GuinganeHepato-Gastroenterology Department, Bogodogo University Hospital Center, Ouagadougou, Burkina Faso.
Asgeir JohannessenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Maud LemoineDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Philippa MatthewsNuffield Department of Medicine, University of Oxford, Oxford, UK.
Edith OkekeFaculty of Medical Sciences, University of Jos, Jos, Nigeria.
Yusuke ShimakawaEpidemiology of Emerging Diseases Unit, Pastor Institute, Paris, France.
Roger SombieDépartement d'Hépato-gastroentérologie, Yalgado Ouédraogo University Hospital Center, Ouagadougou, Burkina Faso.
Alexander StockdaleDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
Gilles WandelerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Monique AnderssonDivision of Medical Virology, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa.
Pantong DavwarFaculty of Medical Sciences, University of Jos, Jos, Nigeria.
Hailemichael DesalegnMedical Department, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Mary DuguruFaculty of Medical Sciences, University of Jos, Jos, Nigeria.
Fatou FallDepartment of Hepatology and Gastroenterology, Dakar Main Hospital, Dakar, Senegal.
Tongai MapongaDivision of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
David Nyam PaulFaculty of Medical Sciences, University of Jos, Jos, Nigeria.
Moussa SeydiDepartment of Infectious and Tropical Diseases, Regional Center for Research and Training, Fann National University Hospital Center, Dakar, Senegal.
Edford SinkalaDepartment of Internal Medicine, University of Zambia, Lusaka, Zambia.
Jantjie TaljaardDivision of Infectious Diseases, Department of Medicine, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa.
Mark SonderupDivision of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
C Wendy SpearmanDivision of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-3199-301X
University of Jos · NGStellenbosch University · ZAUniversity of Cape Town · ZAUniversity of Zambia · ZMCentre Hospitalier National Universitaire de Fann · SNCentre Hospitalier Universitaire Yalgado Ouédraogo · BFHôpital Principal de Dakar · SNImperial College London · GBInstitut Pasteur · FRLiverpool School of Tropical Medicine · GBSt. Paul's Hospital Millennium Medical College · ETUniversity of Bern · CHUniversity of Liverpool · GBUniversity of Oslo · NOUniversity of Oxford · GB

Funding

Mechanisms of HBV Functional Cure During Tenofovir-based ART in HIV/HBV CoinfectionR01AI147727 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael Jeffrey Vinikoor · 2019 to 2026
$3.9M
NIAID NIH HHS R01 AI147727
6 · The paper itself

Abstract

Approximately 80 million people live with chronic hepatitis B virus (HBV) infection in the WHO Africa Region. The natural history of HBV infection in this population is poorly characterised, and may differ from patterns observed elsewhere due to differences in prevailing genotypes, environmental exposures, co-infections, and host genetics. Existing research is largely drawn from small, single-centre cohorts, with limited follow-up time. The Hepatitis B in Africa Collaborative Network (HEPSANET) was established in 2022 to harmonise the process of ongoing data collection, analysis, and dissemination from 13 collaborating HBV cohorts in eight African countries. Research priorities for the next 5 years were agreed upon through a modified Delphi survey prior to baseline data analysis being conducted. Baseline data on 4,173 participants with chronic HBV mono-infection were collected, of whom 38.3% were women and the median age was 34 years (interquartile range 28-42). In total, 81.3% of cases were identified through testing of asymptomatic individuals. HBeAg-positivity was seen in 9.6% of participants. Follow-up of HEPSANET participants will generate evidence to improve the diagnosis and management of HBV in this region.

Indexed as

Hepatitis BHepatitis B, ChronicAdultAfricaFemaleHepatitis B e AntigensHepatitis B virusHumansMaleHepatitis B e AntigensAfricaantiviral agentsEpidemiologyhepatitis Bhepatocellular carcinomaliver cirrhosis

Identifiers

PMID37009881
PMCPMC10204139
OpenAlexW4362506636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.