Evidence map›Paper›PMID 37009510›Full record

ArticleFrontiers in cellular and infection microbiology2023

GSDMD-mediated pyroptosis restrains intracellular

Ping Jiang, Hongzhi Chen, Xiaojing Feng, Huiqi Xie, Mengjie Jiang, Danning Xu, Haoneng Tang, Ningjie Zhang, Jianlin Chen, Lei Zhang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. HIV-1 andmSphere · 2026
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  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ping JiangDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hongzhi ChenNational Clinical Research Center for Metabolic Disease, Key Laboratory of Diabetes Immunology, Ministry of Education, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xiaojing FengDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Huiqi XieDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Mengjie JiangDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Danning XuDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Haoneng TangDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ningjie ZhangDepartment of Blood Transfusion, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jianlin ChenReproductive Medicine Center, Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Lei ZhangDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Lingli TangDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Second Xiangya Hospital of Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyroptosis, a type of programmed necrosis associated with inflammatory, is a host defense mechanism against microbial infections. Although Chlamydia has been shown to induce pyroptosis, whether pyroptosis directly impacts the growth of Chlamydia has not been demonstrated. In this study, we found that

Indexed as

Intracellular Signaling Peptides and ProteinsPyroptosisAnimalsCaspase 1CaspasesChlamydia trachomatisMacrophagesMiceCaspase 1CaspasesIntracellular Signaling Peptides and Proteinscaspase-1caspase-11Chlamydia trachomatisGSDMDmacrophagepyroptosis

Identifiers

PMID37009510
PMCPMC10061094
OpenAlexW4327619191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.