Evidence map›Paper›PMID 37009413›Full record

ArticleMedComm2023

Genome-wide association study of tuberculosis in the western Chinese Han and Tibetan population.

Hao Bai, Mengyuan Song, Shikun Lei, Lin Jiao, Xuejiao Hu, Tao Wu, Jiajia Song, Tangyuheng Liu, Wu Peng, Zhenzhen Zhao and 2 more

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In one paragraph

Article in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Methylation inImmunoTargets and therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hao BaiDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.ORCID https://orcid.org/0000-0002-0916-5755
Mengyuan SongDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Shikun LeiState Key Laboratory of Biotherapy and Cancer Center West China Hospital Sichuan University Chengdu P. R. China.
Lin JiaoDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Xuejiao HuDivision of Laboratory Medicine Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou P. R. China.
Tao WuDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Jiajia SongDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Tangyuheng LiuDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Wu PengDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Zhenzhen ZhaoDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Zirui MengDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.
Binwu YingDepartment of Laboratory Medicine West China Hospital Sichuan University Chengdu P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) remains a serious global public health threat. Accumulated evidence has demonstrated that human susceptibility to TB has a strong genetic basis. And different susceptibility single nucleotide polymorphisms (SNP) have been reported in different studies. To gain greater insight into the host susceptibility to TB, we perform a two-stage genome-wide association study to identify the susceptible loci of TB. In the discovery stage, 3116 (1532 TB patients and 1584 healthy controls) and 439 (211 TB patients and 228 healthy controls) individuals were genome-wide genotyped from a western Chinese Han and Tibetan population, respectively. Based on the additive genetic model, we discovered 14 and three independent loci that had potential associations with TB susceptibility in the Chinese Han and Tibetan populations, respectively (

Indexed as

genome‐wide association studyhuman leukocyte antigensusceptibilitytuberculosis

Identifiers

PMID37009413
PMCPMC10050958

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.