Evidence map›Paper›PMID 37009023›Full record

ArticleERJ open research2023

Hyperoxia improves exercise capacity in cardiopulmonary disease: a series of randomised controlled trials.

Julian Müller, Mona Lichtblau, Stéphanie Saxer, Simon R Schneider, Paula Appenzeller, Meret Bauer, Elisabeth D Hasler, Esther I Schwarz, Konrad E Bloch, Silvia Ulrich

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Julian MüllerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-4059-5937
Mona LichtblauDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-4485-1758
Stéphanie SaxerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-3278-6277
Simon R SchneiderDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-3635-0515
Paula AppenzellerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Meret BauerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Elisabeth D HaslerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Esther I SchwarzDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Konrad E BlochDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Silvia UlrichDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-5250-5022
University of Zurich · CHUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to investigate the overall and differential effect of breathing hyperoxia (inspiratory oxygen fraction ( Methods: 91 subjects (32 healthy, 22 with PVD with pulmonary arterial or distal chronic thromboembolic PH, 20 with COPD, 10 with PH in HFpEF and seven with CHD) performed two cycle incremental (IET) and two constant work-rate exercise tests (CWRET) at 75% of maximal load (W Results: Overall, hyperoxia increased W Conclusion: This large sample of healthy subjects and patients with various cardiopulmonary diseases confirms that hyperoxia significantly prolongs cycling exercise with improvements being highest in endurance CWRET and patients with PVD. These results call for studies investigating optimal oxygen levels to prolong exercise time and effects on training.

Identifiers

PMID37009023
PMCPMC10052458
OpenAlexW4318070657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.