Evidence map›Paper›PMID 37008785›Full record

ArticleFrontiers in molecular neuroscience2023

Excessive self-grooming, gene dysregulation and imbalance between the striosome and matrix compartments in the striatum of

Allain-Thibeault Ferhat, Elisabeth Verpy, Anne Biton, Benoît Forget, Fabrice De Chaumont, Florian Mueller, Anne-Marie Le Sourd, Sabrina Coqueran, Julien Schmitt, Christelle Rochefort and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome.Autism research : official journal of the International Society for Autism Research · 2025
    Review
  3. Review
  4. Article
  5. Convergence of autism proteins at the cilium.bioRxiv : the preprint server for biology · 2025
    Article
  6. Behavioral decline in Shank3Molecular autism · 2024
    Article
  7. Behavioral regression in shank3Research square · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 3 countries.

Allain-Thibeault FerhatGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Elisabeth VerpyGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Anne BitonBioinformatics and Biostatistics Hub, Institut Pasteur, Université Paris Cité, Paris, France.
Benoît ForgetGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Fabrice De ChaumontGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Florian MuellerImagerie et Modélisation, Institut Pasteur, CNRS UMR 3691, Paris, France.
Anne-Marie Le SourdGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Sabrina CoqueranGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Julien SchmittCerebellum Navigation and Memory Team, Institut de Biologie Paris Seine, Neurosciences Paris Seine, CNRS UMR 8246, Inserm UMR-S 1130, Sorbonne Université, Paris, France.
Christelle RochefortCerebellum Navigation and Memory Team, Institut de Biologie Paris Seine, Neurosciences Paris Seine, CNRS UMR 8246, Inserm UMR-S 1130, Sorbonne Université, Paris, France.
Laure Rondi-ReigCerebellum Navigation and Memory Team, Institut de Biologie Paris Seine, Neurosciences Paris Seine, CNRS UMR 8246, Inserm UMR-S 1130, Sorbonne Université, Paris, France.
Aziliz LeboucherGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Anne BolandCentre National de Recherche en Génomique Humaine, CEA, Université Paris-Saclay, Evry, France.
Bertrand FinCentre National de Recherche en Génomique Humaine, CEA, Université Paris-Saclay, Evry, France.
Jean-François DeleuzeCentre National de Recherche en Génomique Humaine, CEA, Université Paris-Saclay, Evry, France.
Tobias M BoeckersInstitute of Anatomy and Cell Biology, Ulm University, Ulm, Germany.
Elodie EyGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Thomas BourgeronGénétique Humaine et Fonctions Cognitives, Institut Pasteur, CNRS UMR 3571, IUF, Université Paris Cité, Paris, France.
Centre National de la Recherche Scientifique · FRUniversité Paris Cité · FRInstitut Pasteur · FRCEA Paris-Saclay · FRCentre National de Recherche en Génomique Humaine · FRColumbia University Irving Medical Center · USCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInserm · FRInstitut de Biologie Paris-Seine · FRNeurosciences Paris-Seine · FRUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism is characterized by atypical social communication and stereotyped behaviors. Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are detected in 1-2% of patients with autism and intellectual disability, but the mechanisms underpinning the symptoms remain largely unknown. Here, we characterized the behavior of

Indexed as

autismGAD65matrixmouse modelShank3stereotyped behaviorstriatum compartmentationstriosomes

Identifiers

PMID37008785
PMCPMC10061084
OpenAlexW4327616659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.