Evidence map›Paper›PMID 37008716›Full record

ArticleFrontiers in ecology and evolution2022

Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration.

Tom Humphreys, Keith Weiser, Asuka Arimoto, Akane Sasaki, Gene Uenishi, Brent Fujimoto, Takeshi Kawashima, Kekoa Taparra, Janos Molnar, Noriyuki Satoh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in ecology and evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. A wound-induced differentiation trajectory for neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Tom HumphreysInstitute for Biogenesis Research, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Keith WeiserInstitute for Biogenesis Research, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Asuka ArimotoMarine Biological Laboratory, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, Japan.
Akane SasakiMarine Biological Laboratory, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, Japan.
Gene UenishiInstitute for Biogenesis Research, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Brent FujimotoInstitute for Biogenesis Research, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Takeshi KawashimaMarine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Kekoa TaparraInstitute for Biogenesis Research, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Janos MolnarInstitute for Biogenesis Research, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Noriyuki SatohMarine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Yusuke MarikawaInstitute for Biogenesis Research, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Kuni TagawaMarine Biological Laboratory, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, Japan.
University of Hawaiʻi at Mānoa · USHiroshima University · JPOkinawa Institute of Science and Technology Graduate University · JP

Funding

USING EEG COMPLEXITY AND HIGH PERFORMANCE COMPUTING TO PROFILE SLEEPP20RR016467 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI HOLMES, ERIC · 2001 to 2011
$24.5M
Training in Cardiovascular Research at the University of HawaiiT32HL115505 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI Michelle D Tallquist · 2012 to 2026
$3.8M
Body Plan Formation in Early Mouse EmbryoR01HD040208 · NICHD · UNIVERSITY OF HAWAII AT MANOA · PI MARIKAWA, YUSUKE · 2001 to 2004
$772k
NCRR NIH HHS P20 RR016467NHLBI NIH HHS T32 HL115505NICHD NIH HHS R01 HD040208
6 · The paper itself

Abstract

Hemichordate enteropneust worms regenerate extensively in a manner that resembles the regeneration for which planaria and hydra are well known. Although hemichordates are often classified as an extant phylogenetic group that may hold ancestral deuterostome body plans at the base of the deuterostome evolutionary line leading to chordates, mammals, and humans, extensive regeneration is not known in any of these more advanced groups. Here we investigated whether hemichordates deploy functional homologs of canonical Yamanaka stem cell reprogramming factors,

Indexed as

hemichordatesKlf1/2/4MsxlxPou3regenerationSoxB1stem-cell reprogramming genes

Identifiers

PMID37008716
PMCPMC10065570
OpenAlexW4220673482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.