Evidence map›Paper›PMID 37008706›Full record

ArticleJournal of vitreoretinal diseases

An Evaluation of the Microvasculature of Macular Nodules in Coats Disease Using Optical Coherence Tomography Angiography: A Report of 3 Cases.

Sally S Ong, S Tammy Hsu, Arathi Ponugoti, Cynthia A Toth, Lejla Vajzovic

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of vitreoretinal diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sally S OngWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-3599-9021
S Tammy HsuDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Arathi PonugotiDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Cynthia A TothDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Lejla VajzovicDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Duke University · USJohns Hopkins University · US

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI W Daniel Stamer · 1985 to 2026
$19.3M
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve CareR01EY025009 · NEI · DUKE UNIVERSITY · PI Xi Chen, CYNTHIA ANN TOTH · 2016 to 2026
$6.6M
NEI NIH HHS P30 EY005722NEI NIH HHS R01 EY025009
6 · The paper itself

Abstract

Purpose: This work aimed to examine the microvasculature of macular fibrosis in Coats disease. Methods: Three boys (aged 3, 4, and 6 years) with Coats disease (stages 2B to 3A2) and macular fibrotic nodules were imaged using optical coherence tomography angiography (OCTA) on the Spectralis spectral-domain OCT tabletop and investigational portable Spectralis Flex module (version 6.9, Heidelberg Engineering). Results: In 2 eyes, a neovascular complex was observed in the avascular slab on OCTA. This neovascular complex had vessels connected to diving vessels from the superficial vascular complex that traveled through the deep vascular complex to the avascular complex. In the third eye, no neovascular complex was observed on OCTA at presentation, but on subsequent examinations fluorescein leakage was observed and cross-sectional OCTA further confirmed the presence of angiographic flow in the nodule. Conclusions: OCTA demonstrates the presence of type 3 neovascularization in fibrotic nodules in Coats disease.

Indexed as

Coats diseasefibrosismacular nodulesmicrovasculatureneovascularizationoptical coherence tomography angiography

Identifiers

PMID37008706
PMCPMC9976116
OpenAlexW3128560895

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.