Evidence map›Paper›PMID 37008544›Full record

ArticleJournal of vitreoretinal diseases

Management Patterns and Outcomes for Intravitreal Injection-Related Endophthalmitis.

Srinath Soundararajan, Cason B Robbins, Henry L Feng, Sharon Fekrat

Open access · greenAbstract read
In one paragraph

Article in Journal of vitreoretinal diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Inflammation and Vasculitis Related to Brolucizumab.Journal of clinical medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Srinath SoundararajanDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.ORCID https://orcid.org/0000-0002-7510-3026
Cason B RobbinsDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.ORCID https://orcid.org/0000-0001-7909-510X
Henry L FengDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.ORCID https://orcid.org/0000-0002-6485-609X
Sharon FekratDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.ORCID https://orcid.org/0000-0003-4403-5996
Duke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This work describes the clinical management and outcomes in cases of presumed infectious endophthalmitis following intravitreal injection at a tertiary academic medical center. Methods: A retrospective review took place of eyes that presented to the Duke Eye Center over a 9-year period and were diagnosed with intravitreal injection-related endophthalmitis. Clinical presentation, management, microbiologic yield, visual outcomes, and complications were abstracted from medical records. Results: Of 23 eyes diagnosed with postinjection endophthalmitis, 52.2% underwent anterior chamber tap (33.3% of which first underwent dry needle vitreous tap), 47.8% underwent needle vitreous tap, 17.4% underwent neither, and none underwent pars plana vitrectomy (PPV) for initial management. Subsequent PPV was performed in 6 eyes (26.1%). Mean visual acuity (VA) improved by 50 Early Treatment Diabetic Retinopathy Study letters at 6 months. Eyes that underwent initial anterior chamber tap had worse presenting VA than those that did not ( Conclusions: Eyes with intravitreal injection-related endophthalmitis presenting with VA of hand motion or worse were more likely to undergo subsequent PPV. Future studies with larger cohorts may reveal whether earlier vitrectomy should be considered in these patients.

Indexed as

anti-VEGF injectionendophthalmitisintravitreal injectionintravitreal injection–related endophthalmitispars plana vitrectomy

Identifiers

PMID37008544
PMCPMC9976125
OpenAlexW3183318461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.