ArticleFrontiers in neuroscience2023
Altered neuromagnetic activity in default mode network in childhood absence epilepsy.
Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Salience network hub dysfunction is associated with cognitive impairment in self-limited epilepsy with centrotemporal spikes: An OPM-MEG study.Epilepsia open · 2026Article
- Efficacy of oxcarbazepine in treating focal epilepsy based on resting-state EEG functional connectivity and power spectral analyses.Acta epileptologica · 2026Article
- Fully Automated EEG Source Imaging Using Structured Sparsity for Single and Multiple Synchronous Epileptic Activities.Brain topography · 2026Article
- The effects of unilateral nostril breathing on brain functional network activity: a pilot study.Journal of neuroengineering and rehabilitation · 2025Article
- Absence seizures: Update on signaling mechanisms and networks.Epilepsia open · 2025Article
- Olfactory Epithelium Stimulation Using Rhythmic Nasal Air-Puffs Improves the Cognitive Performance of Individuals with Acute Sleep Deprivation.Brain sciences · 2024Article
- Understanding of Consciousness in Absence Seizures: A Literature Review.Neuropsychiatric disease and treatment · 2024Review
- Involvement of the default mode network in patients with transient global amnesia: multilayer network.Neuroradiology · 2023Article
- Frontal lobe epilepsy: an eye tracking study of memory and attention.Frontiers in neuroscience · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The electrophysiological characterization of resting state oscillatory functional connectivity within the default mode network (DMN) during interictal periods in childhood absence epilepsy (CAE) remains unclear. Using magnetoencephalographic (MEG) recordings, this study investigated how the connectivity within the DMN was altered in CAE. Methods: Using a cross-sectional design, we analyzed MEG data from 33 children newly diagnosed with CAE and 26 controls matched for age and sex. The spectral power and functional connectivity of the DMN were estimated using minimum norm estimation combined with the Welch technique and corrected amplitude envelope correlation. Results: Default mode network showed stronger activation in the delta band during the ictal period, however, the relative spectral power in other bands was significantly lower than that in the interictal period ( Conclusion: These findings indicated DMN abnormalities in CAE patients, even in interictal periods without interictal epileptic discharges. Abnormal functional connectivity in CAE may reflect abnormal anatomo-functional architectural integration in DMN, as a result of cognitive mental impairment and unconsciousness during absence seizure. Future studies are needed to examine if the altered functional connectivity can be used as a biomarker for treatment responses, cognitive dysfunction, and prognosis in CAE patients.
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