Evidence map›Paper›PMID 37007990›Full record

ArticleFrontiers in physiology2023

Metabolic correlates to critical speed in murine models of sickle cell disease.

Francesca I Cendali, Travis Nemkov, Christina Lisk, Ian S Lacroix, Seyed-Mehdi Nouraie, Yingze Zhang, Victor R Gordeuk, Paul W Buehler, David Irwin, Angelo D'Alessandro

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Francesca I CendaliDepartment of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO, United States.
Travis NemkovDepartment of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO, United States.
Christina LiskDepartment of Pulmonology, University of Colorado Denver, Aurora, CO, United States.
Ian S LacroixDepartment of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO, United States.
Seyed-Mehdi NouraieDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Yingze ZhangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Victor R GordeukDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Paul W BuehlerDepartment of Pathology, University of Maryland, Baltimore, MD, United States.
David IrwinDepartment of Pulmonology, University of Colorado Denver, Aurora, CO, United States.
Angelo D'AlessandroDepartment of Pulmonology, University of Colorado Denver, Aurora, CO, United States.
University of Colorado Denver · USUniversity of Pittsburgh · USUniversity of Illinois Chicago · USUniversity of Maryland, Baltimore · US

Funding

VRAC and Rho in pulmonary EC proliferationP01HL014985 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STENMARK, KURT R. · 1985 to 2019
$35.1M
Role of Complement-Driven Pulmonary Vascular Inflammation in PHP01HL152961 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DELANEY, CASSIDY A · 2020 to 2024
$14.1M
Translational Pulmonary Vascular Biology ProgramT32HL007171 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Sonia Castro Flores, Tim Lahm · 1985 to 2026
$9.4M
The Impact of Oxidative Stress on Erythocyte BiologyR01HL148151 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI D'ALESSANDRO, ANGELO, KARAFIN, MATTHEW S · 2019 to 2022
$8.9M
The role of ferroptosis in red cell aging in vivo and in vitroR01HL146442 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Angelo D'Alessandro, Adam N. Goldfarb · 2019 to 2026
$5.4M
The paradoxical response to iron in pulmonary hypertension of sickle cell diseaseR01HL161004 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BUEHLER, PAUL WERNER, D'ALESSANDRO, ANGELO · 2022 to 2025
$2.7M
Bioengineering a Dual Function Protein Construct to Detoxify Heme and HemoglobinR01HL159862 · NHLBI · OHIO STATE UNIVERSITY · PI BUEHLER, PAUL WERNER, CABRALES, PEDRO · 2021 to 2024
$2.6M
Aerosolized therapy for hemoglobin toxicity in the treatment of hemolytic diseasesR01HL158076 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BUEHLER, PAUL WERNER, IRWIN, DAVID CHARLES · 2022 to 2025
$2.5M
The contribution of free hemoglobin in the progression of pulmonary remodelingR01HL125642 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI IRWIN, DAVID CHARLES · 2015 to 2019
$1.9M
BLRD VA I01 BX002042NHLBI NIH HHS P01 HL014985NHLBI NIH HHS P01 HL152961NHLBI NIH HHS R01 HL125642NHLBI NIH HHS R01 HL146442NHLBI NIH HHS R01 HL148151NHLBI NIH HHS R01 HL158076NHLBI NIH HHS R01 HL159862NHLBI NIH HHS R01 HL161004NHLBI NIH HHS T32 HL007171
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

carnitinescritical speedexercisemetabolismsickle cell disease

Identifiers

PMID37007990
PMCPMC10053510
OpenAlexW4324085358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.