Evidence map›Paper›PMID 37007877›Full record

ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2023

The Role of Serum Galactomannan Assay as a Potential Surrogate Biomarker for Fungal Microinvasion in Allergic Fungal Rhinosinusitis.

Anupam Kanodia, Ashu Seith Bhalla, Gagandeep Singh, Immaculata Xess, Bashid Valia Valappil, Aanchal Kakkar, Shilpi Budhiraja, Kapil Sikka, David Victor Kumar Irugu, Alok Thakar and 1 more

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In one paragraph

Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Anupam KanodiaDepartment of Otorhinolaryngology and Head-Neck Surgery, Room no 4057, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029 India.ORCID 0000-0002-3933-0416
Ashu Seith BhallaDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Gagandeep SinghDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Immaculata XessDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Bashid Valia ValappilDepartment of Otorhinolaryngology and Head-Neck Surgery, Room no 4057, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029 India.
Aanchal KakkarDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Shilpi BudhirajaDepartment of Otorhinolaryngology and Head-Neck Surgery, Room no 4057, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029 India.
Kapil SikkaDepartment of Otorhinolaryngology and Head-Neck Surgery, Room no 4057, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029 India.ORCID 0000-0002-3457-4518
David Victor Kumar IruguDepartment of Otorhinolaryngology and Head-Neck Surgery, Room no 4057, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029 India.
Alok ThakarDepartment of Otorhinolaryngology and Head-Neck Surgery, Room no 4057, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029 India.
Hitesh VermaDepartment of Otorhinolaryngology and Head-Neck Surgery, Room no 4057, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029 India.ORCID 0000-0001-7905-3073
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted this study to determine if serum galactomannan (GM) can be used as a marker to implicate the invasiveness of allergic fungal rhinosinusitis (AFRS), and correlate this value with the aggressiveness of disease documented via computed tomography (CT). All paranasal CT scans done for AFRS patients prospectively over a five-year period (2015-2019) were included. An indigenous 20-point score was used to document the extent of bone erosion seen on CT, wherein a higher score meant a greater extent of bone erosion. It was then correlated with serum GM scores. The median CT scores of galactomannan-positive (GM+) patients were compared with the median CT scores of galactomannan-negative (GM-) patients 3 using Mann-Whitney U test. The patients were divided into five groups based on the extent of disease-No bone erosion, erosion of only sinus wall/orbit, 3 erosion of orbit and skull base, erosion of only skull base and lateral extension of disease into infratemporal fossa (ITF). Subgroup analysis was conducted over mean GM values in these groups using ANOVA test.

Indexed as

AFRSFungal sinusitisRhinosinusitis

Identifiers

PMID37007877
PMCPMC10050302
OpenAlexW4318426323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.