Evidence map›Paper›PMID 37007769›Full record

ArticleFrontiers in medicine2023

Relationship between fibrinogen level and advanced colorectal adenoma among inpatients: A retrospective case-control study.

Huijie Wang, Huanwei Zheng, Xu Cao, Ping Meng, Jinli Liu, Zhichao Wang, Teng Zhang, Haiying Zuo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Huijie WangDepartment of Endoscopy, Shijiazhuang Traditional Chinese Medicine Hospital, Shijiazhuang, China.
Huanwei ZhengDepartment of Gastroenterology, Shijiazhuang Traditional Chinese Medicine Hospital, Shijiazhuang, China.
Xu CaoDepartment of Endoscopy, Shijiazhuang Traditional Chinese Medicine Hospital, Shijiazhuang, China.
Ping MengDepartment of Gastroenterology, Shijiazhuang Traditional Chinese Medicine Hospital, Shijiazhuang, China.
Jinli LiuDepartment of Endoscopy, Shijiazhuang Traditional Chinese Medicine Hospital, Shijiazhuang, China.
Zhichao WangGraduate School, Hebei North University, Zhangjiakou, China.
Teng ZhangInstitute of Traditional Chinese Medicine, North China University of Science and Technology, Tangshan, China.
Haiying ZuoGraduate School, Hebei North University, Zhangjiakou, China.
Jining Traditional Chinese Medicine Hospital · CNHebei North University · CNNorth China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study was to explore the relationship between fibrinogen and advanced colorectal adenoma among inpatients. Methods: From April 2015 to June 2022, 3738 participants (566 case subjects and 3172 control subjects) who underwent colonoscopies enrolled, and smooth curve fitting and logistic regression models were applied to explore the association between fibrinogen and advanced colorectal adenoma. In addition, sensitivity and subgroup analyses were performed to assess the stability of the results. Results: Compared with lower fibrinogen quantile 1 (< 2.4 g/L), the adjusted OR values for fibrinogen and advanced colorectal adenoma in quantile 2 (2.4-2.75 g/L), quantile 3 (2.76-3.15 g/L), and quantile 4 (≥3.16 g/L) were 1.03 (95% confidence interval [CI]: 0.76-1.41), 1.37 (95% CI: 1.01-1.85), and 1.43 (95% CI: 1.06-1.94), respectively. A linear relationship between fibrinogen and advanced colorectal adenoma was observed. Sensitivity and subgroup analyses showed stable results. Conclusion: Complements the evidence that fibrinogen was positively associated with advanced adenomas, suggesting that fibrinogen may play a role in the adenoma-carcinoma sequence.

Indexed as

advanced colorectal adenomaassociationcase-control studyfibrinogenretrospective study

Identifiers

PMID37007769
PMCPMC10061582
OpenAlexW4327593480

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.