Evidence map›Paper›PMID 37007694›Full record

ArticleClinical kidney journal2023

Interaction effect between fasting plasma glucose and lipid profiles on mortality of peritoneal dialysis patients.

Yiping Xu, Zhong Zhong, Yi Li, Zhijian Li, Yi Zhou, Zhibin Li, Haiping Mao

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yiping XuDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhong ZhongDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yi LiDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhijian LiDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yi ZhouDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhibin LiEpidemiology Research Unit, Translational Medicine Research Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Haiping MaoDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peritoneal dialysis (PD) patients have a high risk of abnormal glucose and lipids metabolism. Objective: We investigated the effects of baseline fasting plasma glucose (FPG) as well as its interaction with lipid profiles on all-cause and cardiovascular disease (CVD) cause-specific mortality in PD patients. Methods: A total of 1995 PD patients were enrolled. Kaplan-Meier survival curves and Cox regression models were performed to assess the association of FPG levels with mortality in PD patients. Results: During a median (25th-75th quartile) follow-up period of 48.1 (21.8-77.9) months, 567 (28.4%) patients died, including 282 (14.1%) CVD deaths. Kaplan-Meier survival curves showed that all-cause and CVD cause-specific mortality increased significantly with elevated baseline FPG levels (Log-rank tests: both Conclusion: The significant interaction effect between baseline FPG and LDL-C on all-cause mortality showed that, for PD patients with LDL-C ≥3.37 mmol/L, higher FPG levels (≥7.0 mmol/L) were significantly associated with an increased risk of all-cause mortality and need more intensive management of their FPG by clinicians in the future.

Indexed as

fasting plasma glucoseinteractionlow-density lipoprotein cholesterolmortalityperitoneal dialysis

Identifiers

PMID37007694
PMCPMC10061421
OpenAlexW4311734052

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.